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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Li Sa Zhao YongGang Zhang ZhiQi Xu Yuhong |
| Copyright Year | 2001 |
| Description | Author affiliation: Dept. of Bio-medical Eng., Shanghai Jiao Tong Univ., China (Li Sa; Zhao YongGang; Zhang ZhiQi; Xu Yuhong) |
| Abstract | Paclitaxel stabilizes microtubules while inhibits mitotic spindle formation. It has been found to be effective in treating several solid cancers. The aim of this study was to incooperate paclitaxel in conventional and PEGylated liposomes, and to evaluate the antiproliferative effects of different formulations on MCF-7 and ZR75-1 cell lines. MTT assay was used to determine the growth inhibition of the cell line by paclitaxel. A significant dose-dependent inhibition of proliferation was found after the cells were exposured to certain liposomal paclitaxel preparations, suggesting the possible use of liposomes as effective palitaxel delivery devices. |
| Starting Page | 2931 |
| Ending Page | 2933 |
| File Size | 219620 |
| Page Count | 3 |
| File Format | |
| ISBN | 0780372115 |
| ISSN | 1094687X |
| DOI | 10.1109/IEMBS.2001.1017405 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2001-10-25 |
| Publisher Place | Turkey |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Vehicles Drugs Solids Breast cancer Breast neoplasms Tumors Cells (biology) Automotive engineering Educational institutions Biotechnology |
| Content Type | Text |
| Resource Type | Article |
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