NDLI: Investigating the spatial and temporal interactions in resting-state fMRI with total activation

Content Provider	IEEE Xplore Digital Library
Author	Karahanoglu, F.I. Van De Ville, D.
Copyright Year	2014
Description	Author affiliation: Inst. of Bioeng., Ecole Polytech. Fed. de Lausanne (EPFL), Lausanne, Switzerland (Karahanoglu, F.I.; Van De Ville, D.)
Abstract	Resting-state functional magnetic resonance imaging (fMRI) has become an important tool to study the spontaneous brain fluctuations. Especially, in terms of network analysis, the intrinsic brain activations have been shown to exhibit some characteristic spatial patterns referred to as resting-state networks. These distinct networks, which are mostly distinguished by their spatial distribution, have been proven to be reproducible via different fMRI data analysis techniques. However, the spatial and temporal interactions in the resting-state fMRI data are merely investigated. It is necessary to investigate the temporal evolution of the “bursts” of activations or the “switching” of different (probably overlapping) networks for better understanding of brain's intrinsic organization. Recently, we have proposed total activation (TA) which reveals the “underlying” activity-patterns in fMRI without incorporating any prior model of the events' onsets and durations. TA is cast as a spatio-temporal regularization where it promotes the sparsity of the innovation signals, which delineate the onsets and offsets of transient activations in each voxel. In this work, we study the temporal and spatial interactions of the synchronized “burst” of activations captured by TA.
Starting Page	588
Ending Page	591
File Size	1813239
Page Count	4
File Format	PDF
ISBN	9781467319614
DOI	10.1109/ISBI.2014.6867939
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2014-04-29
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Technological innovation Correlation Transient analysis Magnetic resonance imaging Hemodynamics Biomedical imaging Brain modeling network dynamics fMRI BOLD spatio-temporal regularization clustering synchronous networks
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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