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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Posada, M.M. Shedden, K. Young-Tae Chang Qian Li Rosania, G.R. |
| Copyright Year | 2007 |
| Description | Author affiliation: Dept. of Pharm. Sci., Michigan Univ., Ann Arbor, MI (Posada, M.M.) |
| Abstract | Cheminformatic assisted image array (CAIA) is a data mining and visualization tool linking chemical structures to microscope images of cells incubated with prospective bioimaging probes. In a CAIA, machine vision can be used to calculate the quantitative contribution of the chemical features of candidate probes to the apparent image features. In turn, image arrays can be constructed and sorted based on the features of molecules or images, so that the contribution of chemical features on visual features of the images can be readily discerned, across a large data set. By enabling visualization of complex multidimensional relationships between chemical structures and visual signals, CAIA can facilitate the search for new classes of fluorescent probes of cell structure and function. |
| Starting Page | 1108 |
| Ending Page | 1111 |
| File Size | 357653 |
| Page Count | 4 |
| File Format | |
| ISBN | 1424406714 |
| DOI | 10.1109/ISBI.2007.357050 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2007-04-12 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Probes Fluorescence Chemicals Pixel Image analysis Microscopy Extracellular Data visualization Machine vision Signal analysis |
| Content Type | Text |
| Resource Type | Article |
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