NDLI: Modeling and measurement of elastic laminae in arteries

Content Provider	IEEE Xplore Digital Library
Author	Hai Xu Jin-Jia Hu Humphrey, J.D. Jyh-Charn Liu
Copyright Year	2006
Description	Author affiliation: Dept. of Comput. Sci., Texas A&M Univ., College Station, TX (Hai Xu)
Abstract	Analysis of elastic laminae provides vital information on both the gross and fine structures of the arterial wall, which is vital to assess issues such as mechanical damage caused by cardiovascular disease or clinical treatment. For example, the distribution of thickness, and distance between them, of the elastic laminae within the aorta can provide important clues on how hypertension affects aortic structure temporally. The requisite microscopic (i.e., histologic or immunohistologic) images have numerous segments, making their measurement and characterization a laborious and inaccurate task. In this paper, we propose a novel scheme for automated analysis of lamina thickness. Results show that our scheme can accurately orient image samples, and detect and calculate thickness distribution in cross sections of the aorta. This new technique not only drastically reduces the human labor, it also eliminates inevitable errors and inconsistencies of manual measurements
Starting Page	626
Ending Page	629
File Size	1095312
Page Count	4
File Format	PDF
ISBN	078039576X
DOI	10.1109/ISBI.2006.1624994
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-04-06
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Arteries Biomedical imaging Information analysis Cardiovascular diseases Hypertension Microscopy Immune system Image segmentation Humans Manuals
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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