NDLI: Investigation of near-infrared autofluorescence imaging for the detection of breast cancer

Content Provider	IEEE Xplore Digital Library
Author	Demos, S.G. Bold, R. White, Rd.V. Ramsamooj, R.
Copyright Year	1995
Abstract	Detection of breast cancer in fresh tissue obtained from surgery is investigated using near-infrared autofluorescence imaging under laser excitation at 532 and 632.8 nm. The differences in intensity between the three main components of breast tissue (cancer, fibrous, and adipose) are estimated and compared to those obtained from cross-polarized light scattering images recorded under polarized illumination at 700 nm. The optical spectroscopic images for each tissue sample were subsequently compared with the histopathology slides. The experimental results indicate that the intensity of the near-infrared emission is considerably different in breast cancer compared to that of the adjacent nonneoplastic tissues (adipose and fibrous tissue). The experimental results suggest that 632.8-nm excitation offers key advantages compared to 532 nm excitation.
Sponsorship	IEEE Lasers and Electro-Optics Society
Starting Page	791
Ending Page	798
Page Count	8
File Size	483947
File Format	PDF
ISSN	1077260X
Volume Number	11
Issue Number	4
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-07-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cancer detection Breast cancer Optical imaging Laser surgery Oncological surgery Laser excitation Breast tissue Light scattering Optical polarization Lighting tissue diagnostics medical and biological imaging spectroscopic imaging
Content Type	Text
Resource Type	Article
Subject	Atomic and Molecular Physics, and Optics Electrical and Electronic Engineering

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