NDLI: Temporal relationship between left ventricular and arterial system elastances

Content Provider	IEEE Xplore Digital Library
Author	Berger, D.S. Li, J.K.-J.
Copyright Year	1964
Abstract	The authors investigated the temporal relationship of arterial compliance to ventricular elastance of the left ventricle (E/sub lv/(t)) in five open-chest anesthetized dogs, where simultaneous aortic pressure and flow and left-ventricular pressure were measured. E/sub lv/(t) was derived using an elastance-resistance model of the left ventricle. The nonlinear pressure-dependent compliance (C(P)) of the arterial system was incorporated in a three-element Windkessel model and determined by accurate prediction of aortic pressure from aortic flow. The resulting arterial elastance E/sub as/(t) was computed as E/sub as/(t)=1/C(P). Results show that E/sub as/(t) reaches a minimum value at or near the start of ventricular ejection and attains its peak value at or near the time that maximum left ventricular elastance is reached, at end-systole. Numerical simulation of the model demonstrates its ability to adequately reproduce measured pressure and flow. Thus, the arterial system, in terms of elastance, is dynamically and temporally coupled to the left-ventricle during ejection.<>
Sponsorship	IEEE Engineering in Medicine and Biology Society
Page Count	7
File Size	658540
Starting Page	404
Ending Page	410
File Format	PDF
ISSN	00189294
Volume Number	39
Issue Number	4
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1992-04-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Pressure measurement Fluid flow measurement Biomedical measurements Heart Dogs Predictive models Numerical simulation Valves Equations
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

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