NDLI: Cardiovascular variability signals: towards the identification of a closed-loop model of the neural control mechanisms

Content Provider	IEEE Xplore Digital Library
Author	Baselli, G. Cerutti, S. Civardi, S. Malliani, A. Pagani, M.
Copyright Year	1964
Abstract	The authors consider parametric methods for processing cardiovascular signals and try to provide a global, although indirect evaluation of some neural regulatory activities. In particular, the variability signals of the heart rate (under the form of interval tachogram) and arterial blood pressure (systogram) together with respiratory movement signal (respirogram) are considered as inputs to a closed-loop model which describes a few aspects of the physiological interactions among the signals themselves. The identifiability of the transfer function of the model is demonstrated from the joint process black-box description of the signals. A direct identification procedure is proposed dividing the system into two dynamic adjustment models. A few suggestions are deduced on how and where the respirogram enters the model and on the genesis of the 10-s rhythm, parameters relevant to the Starling effect, Windkessel model, and the gain of baroreceptor mechanisms. The approach presented is intended also to provide a general frame for closed-loop identification in different pathophysiological conditions.<>
Sponsorship	IEEE Engineering in Medicine and Biology Society
Page Count	14
File Size	1405332
Starting Page	1033
Ending Page	1046
File Format	PDF
ISSN	00189294
Volume Number	35
Issue Number	12
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1988-12-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cardiology Signal processing Rhythm Heart rate Hafnium Arterial blood pressure Spectral analysis Displays Transfer functions
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

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