NDLI: An Integrated Amplifier With Passive Neutralization of Myoelectric Interference From Neural Recording Tripoles

Content Provider	IEEE Xplore Digital Library
Author	Demosthenous, A. Pachnis, I. Dai Jiang Donaldson, N.
Copyright Year	2001
Abstract	This paper describes an integrated amplifier for neural recording from tripolar electrode books connected in the quasi-tripole arrangement. The same tripole is used in the implant for neural stimulation. To remove myoelectric interference from neural recordings, a resistor-capacitor network is used to balance the electrode impedances in the tripole. The amplifier is programmable (recording mode, passband, gain, and trimming impedance) via a serial peripheral interface. Its front-end instrumentation amplifier employs current feedback to achieve high common-mode rejection ratio. The circuit was implemented in 0.35- μm CMOS technology and occupies an area of ~1.2 mm². In the very-low noise mode, the analog front-end features a maximum of 0.68 μVrms input-referred noise in the passband and consumes ~310 μA from a 3 V supply. The measured common-mode rejection ratio of the instrumentation amplifier (CMRRIA) approaches 100 dB. The effect of component mismatch on the CMRRIA and the noise performance of the instrumentation amplifier are examined. In addition, the recording tripole is analyzed to derive the overall common-mode rejection ratio that is shown to exceed 80 dB. The ability of the neural amplifier to reduce myoelectric interference is demonstrated. The amplifier is also tested with a tripole immersed in saline in the stimulate-record mode.
Sponsorship	IEEE Sensors Council
Starting Page	3236
Ending Page	3248
Page Count	13
File Size	3562314
File Format	PDF
ISSN	1530437X
Volume Number	13
Issue Number	9
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-09-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	tripole Implantable circuits instrumentation amplifier low noise myoelectric interference neural recording neural stimulation stimulator
Content Type	Text
Resource Type	Article
Subject	Instrumentation Electrical and Electronic Engineering

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