NDLI: Feature Selection for Accelerometer-Based Posture Analysis in Parkinson's Disease

Content Provider	IEEE Xplore Digital Library
Author	Palmerini, L. Rocchi, L. Mellone, S. Valzania, F. Chiari, L.
Copyright Year	1997
Abstract	Posture analysis in quiet standing is a key component of the clinical evaluation of Parkinson's disease (PD), postural instability being one of PD's major symptoms. The aim of this study was to assess the feasibility of using accelerometers to characterize the postural behavior of early mild PD subjects. Twenty PD and 20 control subjects, wearing an accelerometer on the lower back, were tested in five conditions characterized by sensory and attentional perturbation. A total of 175 measures were computed from the signals to quantify tremor, acceleration, and displacement of body sway. Feature selection was implemented to identify the subsets of measures that better characterize the distinctive behavior of PD and control subjects. It was based on different classifiers and on a nested cross validation, to maximize robustness of selection with respect to changes in the training set. Several subsets of three features achieved misclassification rates as low as 5%. Many of them included a tremor-related measure, a postural measure in the frequency domain, and a postural displacement measure. Results suggest that quantitative posture analysis using a single accelerometer and a simple test protocol may provide useful information to characterize early PD subjects. This protocol is potentially usable to monitor the disease's progression.
Sponsorship	IEEE Engineering in Medicine and Biology Society IEEE Computer Society
Page Count	10
File Size	768011
Starting Page	481
Ending Page	490
File Format	PDF
ISSN	10897771
Volume Number	15
Issue Number	3
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-05-01
Publisher Place	U.S.A.
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Displacement measurement Acceleration Time measurement Time frequency analysis Frequency conversion posture Accelerometer Parkinson's disease (PD) feature selection
Content Type	Text
Resource Type	Article
Subject	Electrical and Electronic Engineering Computer Science Applications Biotechnology

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