NDLI: DETECT-dual energy transmission estimation CT-for improved attenuation correction in SPECT and PET

Content Provider	IEEE Xplore Digital Library
Author	Guy, M.J. Castellano-Smith, I.A. Flower, M.A. Flux, G.D. Ott, R.J. Visvikis, D.
Copyright Year	1963
Abstract	Accurate attenuation correction is a vital component of any quantitative emission CT (ECT) study, especially /sup 131/I-mIBG SPECT where accurate activity measurements are required for dosimetry calculations. Conventional CT is often used to obtain an attenuation map, which is then scaled to the /sup 131/I emission energy (364 keV). Scaling inaccuracies due to the increased photoelectric component of the attenuation coefficients of bone at CT energies lead to an overestimate of activity. Dual energy CT is more accurate but must be justified against increased cost scan time and dose to the patient. We propose a method (DETECT) of obtaining two attenuation maps from a single CT scan using a conventional CT scanner operating at 120 and 140 kVp for alternate slices. Each map's missing slices are reconstructed using weighted linear interpolation. The effect of the X-ray beam spectrum has been investigated by simulated scaling using the CT spectra and by a phantom study. Assuming a perfect emission detector, segmented abdominal CT data predicts a mean activity overestimate of 2/spl plusmn/3% for DETECT compared to 12/spl plusmn/5% for the standard single energy (120 kVp) CT method when scaled to 364 keV, suggesting that DETECT can offer reliable attenuation correction with no dose or user penalty.
Sponsorship	IEEE Nuclear and Plasma Sciences Society Computer Applications in Nuclear and Plasma Sciences (CANPS) Lawrence Berkeley Lab. Lawrence Livermore Nat. Lab. APS College of William and Mary Continuous Electron Beam Accelerator Facility NASA Defence Nuclear Agency Sandia National Laboratories Jet Propulsion Laboratory Brookhaven Nat. Lab. Lawrence Livermore Nat. Lab IEEE/NPPS Radiat. Effects Committee Defence Nuclear Agency/DoD Sandia National Laboratories/DOE Jet Propulsion Laboratory/NASA Phillips Lab./DoD
Starting Page	1261
Ending Page	1267
Page Count	7
File Size	1056144
File Format	PDF
ISSN	00189499
Volume Number	45
Issue Number	3
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1998-06-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Computed tomography Electrical capacitance tomography Attenuation measurement Dosimetry Bones Costs Interpolation Imaging phantoms Detectors Abdomen
Content Type	Text
Resource Type	Article
Subject	Nuclear and High Energy Physics Electrical and Electronic Engineering Nuclear Energy and Engineering

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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