NDLI: Simulation of Tumor Targeting Enhancement by Amplifying of Targeted Nano-Biosensors Radiation Intensity

Content Provider	IEEE Xplore Digital Library
Author	SalmanOgli, A. Rostami, A.
Copyright Year	1964
Abstract	The main goal of this paper is to enhance the produced intensity radiation of nanoparticles that are functionalized to act as nano-biosensors in the biological applications, such as small tumor targeting and imaging. For example, in the optical imaging of the breast cancer, the numbers of photons that reach to the detector are very small because of the depth of the target and the loss of incident light due to absorption and scattering of the live cells and so on. Hence, the detection of small tumors is very difficult. In this paper, for the first time, the intensity radiation, which is produced by functionalized agents, is amplified so that the number of photons reaching to the detector will astonishingly increase. As an important result of this study, it is shown that by signaling among agents, maximum numbers of agents reach toward tumor site, and therefore, their produced intensities surprisingly increase (>tenfold). The signaling among agents is performed by using the particle swarm optimization algorithm. It is well known that by the use of mentioned approach, the small tumors will be detectable. It is notable that the nontoxic silicon or gold nanoparticles have been used as core of the nano-biosensors and their functionalization have been done by related antibodies and suitable proteins.
Sponsorship	IEEE Engineering in Medicine and Biology Society
Page Count	8
File Size	799286
Starting Page	1328
Ending Page	1335
File Format	PDF
ISSN	00189294
Volume Number	60
Issue Number	5
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-01-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	NIST Scattering Gold Tumors Silicon Absorption Electromagnetic fields quantum dot (QD) Nano-biosensor (NBS) nanoparticles (NPs) particle swarm optimization (PSO)
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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