NDLI: Blood Perfusion Values of Laser Speckle Contrast Imaging and Laser Doppler Flowmetry: Is a Direct Comparison Possible?

Content Provider	IEEE Xplore Digital Library
Author	Binzoni, T. Humeau-Heurtier, A. Abraham, P. Mahe, G.
Copyright Year	1964
Abstract	Laser Doppler flowmetry (LDF) and laser speckle contrast imaging (LSCI) allow the monitoring of microvascular blood perfusion. The relationship between the measurements obtained by these two techniques remains unclear. In the present contribution, we demonstrate, experimentally and theoretically, that skin blood flow measurements obtained by LDF and LSCI techniques cannot be compared directly even after “classical” normalization procedure. This technical problem is generated by the nonlinear relationship existing between LDF and LSCI flow data. The experiments have been performed on five healthy voluntary subjects (forearm) by using repeated ischemia/reperfusion cycles to induce the necessary skin blood flow changes. LDF and LSCI data were simultaneously acquired on the same region of interest. Considering the importance of this problem from the clinical point of view, it is concluded that the definition of new corrected algorithms for LSCI is probably a mandatory step that must be taken into account if LDF and LSCI blood flow have to be compared.
Sponsorship	IEEE Engineering in Medicine and Biology Society
Page Count	7
File Size	848635
Starting Page	1259
Ending Page	1265
File Format	PDF
ISSN	00189294
Volume Number	60
Issue Number	5
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-01-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Blood Biomedical measurements Skin Measurement by laser beam Speckle Doppler effect Instruments skin blood perfusion Human laser Doppler flowmetry (LDF) laser speckle contrast imaging (LSCI)
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

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