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Metabolism during hypodynamia
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Author | Federov, I. V. |
| Copyright Year | 1980 |
| Description | Physical immobilization, inaction due to space travel, a sedentary occupation, or bed confinement due to a chronic illness elicit similar alternations in the metabolism of man and animals (rat, rabbit, dog, mouse). After a preliminary period of weight loss, there is eventually weight gain due to increased lipid storage. Protein catabolism is enhanced and anabolism depressed, with elevated urinary excretion of amino acids, creatine, and ammonia. Glycogen stores are depleted and glyconeogenesis is accelerated. Polyuria develops with subsequent redistribution of body fluids in which the blood volume of the systemic circulation is decreased and that of pulmonary circulation increased. This results in depressed production of vasopressin by the posterior pituitary which further enhances urinary water and salt loss. |
| File Size | 2938030 |
| Page Count | 29 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_19800011503 |
| Archival Resource Key | ark:/13960/t50g8gd63 |
| Language | English |
| Publisher Date | 1980-02-01 |
| Access Restriction | Open |
| Subject Keyword | Aerospace Medicine Proteins Physiological Effects Blood Circulation Immobilization Lipids Hormones Metabolism Hypodynamia Stress Physiology Ntrs Nasa Technical Reports ServerĀ (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Technical Report |