NDLI: Effects of gravitational stress, hypokinesia and hypodynamia on the structure of the vascular bed of the spleen

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Effects of gravitational stress, hypokinesia and hypodynamia on the structure of the vascular bed of the spleen

Content Provider	NASA Technical Reports Server (NTRS)
Author	Nesterenko, N. T.
Copyright Year	1980
Description	The effects of two extreme factors, hypokinesia and hypodynamia, on spleen vascular beds were studied on 180 male and female albino rats. Vessels were studied by roentgenography, microroentgenography, clearing of sections and histology. Gravity stress yielded construction of all links of arterial bed and of order 5-7 veins. Large intraorganic vein diameters changed significantly but erratically. Hypokinesia in early phases produced pronounced spleen size reduction. Veins and arteries constricted along entire length. Later hypokinetic stages showed arteries still constricted; veins began to dilate from week 4 of hypokinesia. Sinuosity, uneven contours and varicose dilations of walls in large arteries and veins occurred. Abrupt changes in parenchyma, e.g., atrophy of folliculi, narrowing of lumen of central arteries from thickening of muscular wall. After exposure to hypokinesia followed by gravitational stress, pronounced lesions such as deformation of vascular wall, including rupture, in all vessels of the spleen vascular bed.
File Size	1822297
Page Count	11
File Format	PDF
Alternate Webpage(s)	http://archive.org/details/NASA_NTRS_Archive_19800010434
Archival Resource Key	ark:/13960/t3rv5c822
Language	English
Publisher Date	1980-02-01
Access Restriction	Open
Subject Keyword	Aerospace Medicine Spleen Cardiovascular System Physiological Effects Gravitational Effects Morphology Hypokinesia Rats Histology Hypodynamia Lesions Stress Physiology Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science
Content Type	Text
Resource Type	Article

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