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Self-Assembly of Cyclodextrin-Coated Nanoparticles:Fabrication of Functional Nanostructures for Sensing and Delivery.
| Content Provider | Europe PMC |
|---|---|
| Author | Cengiz, Busra Gevrek, Tugce Nihal Chambre, Laura Sanyal, Amitav |
| Editor | Kakkar, Ashok |
| Copyright Year | 2023 |
| Abstract | In recent years, the bottom-up approach has emerged as a powerful tool in the fabrication of functional nanomaterials through the self-assembly of nanoscale building blocks. The cues embedded at the molecular level provide a handle to control and direct the assembly of nano-objects to construct higher-order structures. Molecular recognition among the building blocks can assist their precise positioning in a predetermined manner to yield nano- and microstructures that may be difficult to obtain otherwise. A well-orchestrated combination of top-down fabrication and directed self-assembly-based bottom-up approach enables the realization of functional nanomaterial-based devices. Among the various available molecular recognition-based "host-guest" combinations, cyclodextrin-mediated interactions possess an attractive attribute that the interaction is driven in aqueous environments, such as in biological systems. Over the past decade, cyclodextrin-based specific host-guest interactions have been exploited to design and construct structural and functional nanomaterials based on cyclodextrin-coated metal nanoparticles. The focus of this review is to highlight recent advances in the self-assembly of cyclodextrin-coated metal nanoparticles driven by the specific host-guest interaction. |
| Journal | Molecules |
| Volume Number | 28 |
| DOI | 10.3390/molecules28031076 |
| PubMed Central reference number | PMC9919557 |
| Issue Number | 3 |
| PubMed reference number | 36770743 |
| e-ISSN | 14203049 |
| Language | English |
| Publisher | Molecular Diversity Preservation International (MDPI) |
| Publisher Date | 2023-01-20 |
| Access Restriction | Open |
| Subject Keyword | cyclodextrin nanoparticle host–guest interaction self-assembly multivalent interactions supramolecular chemistry |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physical and Theoretical Chemistry Medicine Chemistry Drug Discovery Pharmaceutical Science Analytical Chemistry Molecular Medicine Organic Chemistry |
