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Dynamics of Human Regulatory T Cells in Lung Lavages of Lung Transplant Recipients1
| Content Provider | CiteSeerX |
|---|---|
| Author | Neujahr, David C. Cardona, Adriana C. Ulukpo, Onome Rig, Mark Pelaez, Andres Gal, Anthony A. Force, Seth D. Lawrence, E. Clinton Kirk, Allan D. Larsen, Christian P. |
| Abstract | Background—In spite of advances in the field of lung transplantation, the median survival following lung transplant remains below 5 years. Early rejection is a risk factor for the development of chronic rejection. In animal models of transplant tolerance, regulatory T cells (Tregs) can prevent the establishment of rejection. Methods—This study was designed to explore the dynamics of Tregs focally and systemically in lung transplant recipients. Sequential surveillance bronchoscopy results were available in 51 patients with at least 4 sequential samples recovered from each patient at defined times post transplant. In 36 |
| File Format | |
| Access Restriction | Open |
| Subject Keyword | Human Regulatory Cell Lung Transplant Recipients1 Lung Lavage Sequential Surveillance Bronchoscopy Result Animal Model Median Survival Sequential Sample Lung Transplant Recipient Lung Transplant Defined Time Post Transplant Chronic Rejection Early Rejection Transplant Tolerance Lung Transplantation Regulatory Cell Risk Factor |
| Content Type | Text |
