NDLI: Modeling of Multifunctional Porous Tissue Scaffolds With Continuous Deposition Path Plan

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Modeling of Multifunctional Porous Tissue Scaffolds With Continuous Deposition Path Plan

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Khoda, A. K. M. B. Ibrahim, T. Ozbolat Koc, Bahattin
Copyright Year	2012
Abstract	A novel modeling technique for porous tissue scaffolds with targeting the functionally gradient variational porosity with continuous material deposition planning has been proposed. To vary the porosity of the designed scaffold functionally, medial axis transformation is used. The medial axis of each layers of the scaffold is calculated and used as an internal feature. The medial axis is then used connected to the outer contour using an optimum matching. The desired pore size and hence the porosity have been achieved by discretizing the sub-regions along its peripheral direction based on the pore size while meeting the tissue scaffold design constraints. This would ensure the truly porous nature of the structure in every direction as well as controllable porosity with interconnected pores. Thus the desired controlled variational porosity along the scaffold architecture has been achieved with the combination of two geometrically oriented consecutive layers. A continuous, interconnected and optimized tool-path has been generated for successive layers for additive-manufacturing or solid free form fabrication process. The proposed methodology has been computationally implemented with illustrative examples. Furthermore, the designed example scaffolds with the desired pore size and porosity has been fabricated with an extrusion based bio-fabrication process.
Starting Page	571
Ending Page	577
Page Count	7
File Format	PDF
ISBN	9780791845189
DOI	10.1115/IMECE2012-86926
Volume Number	Volume 2: Biomedical and Biotechnology
Conference Proceedings	ASME 2012 International Mechanical Engineering Congress and Exposition
Language	English
Publisher Date	2012-11-09
Publisher Place	Houston, Texas, USA
Access Restriction	Subscribed
Subject Keyword	Variational porosity Medial axis Internal scaffold architecture Design Tissue scaffolds Extruding Porosity Additive manufacturing Manufacturing Stereolithography Modeling
Content Type	Text
Resource Type	Article

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