NDLI: Dielectrophoretic Mixing With Novel Electrode Geometry

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Kumar, G. Naga Siva Sushanta, K. Mitra Bhattacharjee, Subir
Copyright Year	2009
Abstract	Electrokinetic mixing of analytes at micro-scale is important in several biochemical applications like cell activation, DNA hybridization, protein folding, immunoassays and enzyme reactions. This paper deals with the modeling and numerical simulation of micromixing of two different types of colloidal suspensions based on principle of dielectrophoresis (DEP). A mathematical model is developed based on Laplace, Navier-Stokes, and convection-diffusion-migration equations to calculate electric field, velocity, and concentration distributions, respectively. Mixing of two colloidal suspensions is simulated in a three-dimensional computational domain using finite element analysis considering dielectrophoretic, gravitational and convective (advective)–diffusive forces. Phase shifted AC signal is applied to the alternating electrodes for achieving the mixing of two different colloidal suspensions. The results indicate that the electric field and DEP forces are maximum at the edges of the electrodes and become minimum elsewhere. As compared to curved edges, straight edges of electrodes have lower electric field and DEP forces. The results also indicate that DEP force decays exponentially along the height of the channel. The effect of DEP forces on the concentration profile is studied. It is observed that, the concentration of colloidal particles at the electrodes edges is very less compared to elsewhere. Mixing of two colloidal suspensions due to diffusion is observed at the interface of the two suspensions. The improvement in mixing after applying the repulsive DEP forces on the colloidal suspension is observed. Most of the mixing takes place across the slant edges of the triangular electrodes. The effect of electrode pairs and the mixing length on degree of mixing efficiency are also observed.
Sponsorship	Fluids Engineering Division
Starting Page	463
Ending Page	468
Page Count	6
File Format	PDF
ISBN	9780791843734
DOI	10.1115/FEDSM2009-78260
e-ISBN	9780791838556
Volume Number	Volume 2: Fora
Conference Proceedings	ASME 2009 Fluids Engineering Division Summer Meeting
Language	English
Publisher Date	2009-08-02
Publisher Place	Vail, Colorado, USA
Access Restriction	Subscribed
Subject Keyword	Micromixing Dielectrophoresis Ac electrokinetics Microfluidics Enzymes Computer simulation Microscale devices Electrokinetics Diffusion (physics) Modeling Convection Electrodes Geometry Proteins Dna Particulate matter Finite element analysis Signals Electric fields
Content Type	Text
Resource Type	Article

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