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Content Provider | AK Lectures |
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Description | The blood clotting cascade is an extremely effective and efficient process and this is so for a good reason. A blood rupture can quickly decrease the individual's blood pressure and lead to a medical condition called shock. But what exactly makes the blood clotting cascade so efficient? Its the ability to create many blood clots at a very rapid rate. This is because the blood clotting cascade does not simply consists of a single pathway but rather consists of many different pathways that all lead to the same result - to produce blood clots. In addition, there are several positive feedback mechanisms that are used within this process to greatly amplify the amount of blood clots produced. Thrombin, the enzyme that is used to call upon platelets, form fibrin and activate Factor 13, can also be used in positive feedback loops. Thrombin goes back to the beginning of the cascade and also activates Factor 8, Factor 11 and Factor 5 in an effort to amplify the amount of prothrombinase that is formed. Prothrombinase is a dimer protein that in turn is used to make even more thrombin, which is needed to form the blood clots. |
Language | English |
Access Restriction | Open |
Subject Keyword | Biology reason condition thrombin shock blood clots pathway pathways ability |
Content Type | Video |
Educational Role | Teacher Student |
Educational Use | Self Learning Lecture Reading |
Resource Type | Video Lecture |
Education Level | Under Graduate |
Subject | Diseases |
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