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Diseases Exposed: ESR Test in the Classroom
| Content Provider | TeachEngineering: STEM curriculum for K-12 |
|---|---|
| Author | Rajasekaran, Renuka |
| Copyright Year | 2016 |
| Description | Students demonstrate the erythrocyte sedimentation rate test (ESR test) using a blood model composed of tomato juice, petroleum jelly and olive oil. They simulate different disease conditions, including rheumatoid arthritis, anemia, leukocytosis and sickle-cell anemia, by making appropriate variations in the particle as well as in the fluid matrix. Students demonstrate the erythrocyte sedimentation rate test (ESR test) using a blood model composed of tomato juice, petroleum jelly and olive oil. They simulate different disease conditions, including rheumatoid arthritis, anemia, leukocytosis and sickle-cell anemia, by making appropriate variations in the particle as well as in the fluid matrix. Students measure the ESR for each sample blood model, correlate the ESR values with disease conditions and confirm that diseases alter blood composition and properties. During the activity, students learn that when non-coagulated blood is let to stand in a tube, the red blood cells separate and fall to the bottom of the tube, resulting in a sediment and a clear liquid called serum. The height in millimeters of the clear liquid on top of the sediment in a time period of one hour is taken as the sedimentation rate. If a disease is present, this ESR value deviates from the normal, disease-free value. Different diseases cause different ESR values because blood composition and properties, such as density and viscosity, are altered differently by different diseases. Thus, the ESR test serves as a real-world diagnostic screening test to identify indications of the presence of any diseases in people. |
| Language | English |
| Access Restriction | Open |
| Rights Holder | Regents of The University of Colorado Georgia Institute of Technology |
| Subject Keyword | Chemistry Physical Science Physics Science and Technology Blood Cell Erythrocyte Sedimentation Medical Biomedical Engineering Simulation Biomedical Engineer Settling Heterogeneous Mixture Esr Test Procedure Inflammation Blood Model Diagnostic Erythrocyte Sedimentation Rate Disease Clinical Lab Test Blood Test Inflammatory Disease Diagnosis Lab Test Biomedical Blood Disease Esr Test Sedimentation Sedimentation Rate Clinical Engineering Clinical Engineer Diagnostic Tool Sed Rate |
| Content Type | Text Video |
| Time Required | PT2H15M |
| Education Level | Class IX Class X Class XI Class XII |
| Pedagogy | Experimental Activity Lecture cum Demonstration |
| Resource Type | Hands-on |
| Subject | Physics Chemistry Technical |
