NDLI: Validation of the ABCD3-I score to predict stroke risk after transient ischemic attack.

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Validation of the ABCD3-I score to predict stroke risk after transient ischemic attack.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Fang, Hui Gao, Yuan Zhao, Lu Xu, Yuming Lu, Jiameng Tan, Song Sun, Shilei Song, Bo Chandra, Avinash Wang, Ruihao
Description	Country affiliation: China Author Affiliation: Song B ( Department of Neurology, the First Affiliated Hospital of Zhengzhou University, No.1 Jianshe E Rd, Erqi District, Zhengzhou, Henan Province, China.)
Abstract	BACKGROUND AND PURPOSE: The Age, Blood Pressure, Clinical Features, Duration, and Diabetes plus Dual TIA (ABCD(3)-I) score is recommended to predict the risk of early stroke after transient ischemic attack. The aim of this study was to validate the predictive value of the ABCD(3)-I score and compare the accuracy of the Age, Blood Pressure, Clinical Features, Duration, and Diabetes (ABCD(2)) and ABCD(3)-I scores in a Chinese population. METHODS: Data were prospectively collected from patients who had transient ischemic attack, as defined by the World Health Organization time-based criteria. ABCD(2) and ABCD(3)-I scores were available within 7 days of the index transient ischemic attack. The predictive outcome was stroke occurrence at 90 days. The receiver-operating characteristic curves were plotted, and the C statistics were calculated as a measure of predictive ability. The comparison of the area under the receiver-operating characteristic curve (area under the curve) was performed by Z test. RESULTS: Among 239 eligible patients, the mean age was 57.4±13.32 years, and 40.2% of the patients were women. The incidence of stroke at 90 days was 12.1%, which ranged from 0% in patients with lower ABCD(3)-I scores (0-3) to 40.91% in those with higher scores of 8 to 13 (P for trend <0.0001). Moreover, the C statistic of ABCD(3)-I scores (0.825; 95% confidence interval, 0.752-0.898) was statistically higher than that of ABCD(2) scores (0.694; 95% confidence interval, 0.601-0.786; P<0.001). CONCLUSIONS: The ABCD(3)-I score had a higher predictive value than the ABCD(2) score for assessing the risk of early stroke after transient ischemic attack in a Chinese population.
ISSN	00392499
e-ISSN	15244628
Journal	Stroke
Issue Number	5
Volume Number	44
Language	English
Publisher	Lippincott Williams & Wilkins (on behalf of the American Heart Association)
Publisher Date	2013-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Ischemic Attack, Transient Complications Stroke Etiology Epidemiology Predictive Value Of Tests Prospective Studies Risk Assessment Severity Of Illness Index Time Factors Research Support, Non-u.s. Gov't Validation Studies Discipline Cardiology
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine Neuroscience Advanced and Specialized Nursing Neurology (clinical)

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