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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Lope, Virginia Pollán, Marina Pérez-Gómez, Beatriz Boldo, Elena López-Abente, Gonzalo García-Pérez, Javier Ramis, Rebeca Vidal, Enrique Aragonés, Nuria |
| Spatial Coverage | Spain |
| Description | Country affiliation: Spain Author Affiliation: García-Pérez J ( Environmental and Cancer Epidemiology Unit, National Center for Epidemiology, Carlos III Institute of Health, C/Sinesio Delgado 6, 28029 Madrid, Spain. jgarcia@isciii.es) |
| Abstract | BACKGROUND: Installations that burn fossil fuels to generate power may represent a health problem due to the toxic substances which they release into the environment. OBJECTIVES: To investigate whether there might be excess mortality due to tumors of lung, larynx and bladder in the population residing near Spanish combustion installations included in the European Pollutant Emission Register. METHODS: Ecologic study designed to model sex-specific standardized mortality ratios for the above three tumors in Spanish towns, over the period 1994-2003. Population exposure to pollution was estimated on the basis of distance from town of residence to pollution source. Using mixed Poisson regression models, we analyzed: risk of dying from cancer in a 5-kilometer zone around installations that commenced operations before 1990; effect of type of fuel used; and risk gradient within a 50-kilometer radius of such installations. RESULTS: Excess mortality (relative risk, 95% confidence interval) was detected in the vicinity of pre-1990 installations for lung cancer (1.066, 1.041-1.091 in the overall population; 1.084, 1.057-1.111 in men), and laryngeal cancer among men (1.067, 0.992-1.148). Lung cancer displayed excess mortality for all types of fuel used, whereas in laryngeal and bladder cancer, the excess was associated with coal-fired industries. There was a risk gradient effect in the proximity of a number of installations. CONCLUSIONS: Our results could support the hypothesis of an association between risk of lung, laryngeal and bladder cancer mortality and proximity to Spanish combustion installations. |
| ISSN | 00489697 |
| Issue Number | 8 |
| Volume Number | 407 |
| e-ISSN | 18791026 |
| Journal | Science of The Total Environment |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2009-04-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Laryngeal Neoplasms Mortality Lung Neoplasms Power Plants Urinary Bladder Neoplasms Coal Environmental Exposure Fossil Fuels Humans Petroleum Poisson Distribution Regression Analysis Risk Assessment Risk Factors Spain Epidemiology Journal Article Research Support, Non-u.s. Gov't Discipline Environmental Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Environmental Chemistry Waste Management and Disposal Pollution Environmental Engineering |
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