Please wait, while we are loading the content...
| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Machulek, Amilcar de Melo da Silva, Lucas de Oliveira, Silvio Cesar Falcao Dantas, Renato Pereira Cavalcante, Rodrigo Gozzi, Fábio Fabbro Cunha, Rebeca |
| Description | Country affiliation: Brazil Author Affiliation: de Melo da Silva L ( Institute of Chemistry, Federal University of Mato Grosso do Sul); Pereira Cavalcante R ( Institute of Chemistry, Federal University of Mato Grosso do Sul); Fabbro Cunha R ( Institute of Chemistry, Federal University of Mato Grosso do Sul); Gozzi F ( Institute of Chemistry, Federal University of Mato Grosso do Sul); Falcao Dantas R ( School of Technology, University of Campinas); de Oliveira SC ( Institute of Chemistry, Federal University of Mato Grosso do Sul); Machulek A ( Institute of Chemistry, Federal University of Mato Grosso do Sul) |
| Abstract | This study employed direct UV-ABC photolysis and the UV-ABC/H O process to investigate the degradation of tolfenamic acid (TA), a common anti-inflammatory drug used in both human and veterinary medicine. A 2 factorial design with added center point was used to evaluate the effect of three independent variables-namely, H O concentration ([H O ]), TA concentration ([TA]), and experiment time (time)-on TA degradation and H O photolysis during UV-ABC/H O treatment using a high-pressure mercury vapor lamp (photon flux of 2.6307 × 10 J s ) as the UV irradiation source. The responses yielded similar values, revealing a linear behavior, with correlation coefficients R = 0.9968 and R = 0.9921 for TA degradation and R = 0.9828 and R = 0.9570 for H O photolysis. The most efficient combination of variables was [H O ] = 255 mg L and [TA] = 25 mg L , resulting in 100% TA degradation and 98.87% H O photolysis by 90 min of treatment. Additionally, the second-order kinetic constant of the reaction between TA and HO was determined using a competitive kinetic model, employing 2,4-dichlorophenoxyacetic acid (2,4D) as the reference compound. The kinetic constant was 1.9 × 10 M s in alkaline medium. TA degradation by direct photolysis generated quinone imines as by-products, responsible for the formation of a dark red 'internal filter' that increased the value of acute toxicity to Artemia salina. The UV-ABC/H O process did not promote formation of quinone imines by 90 min of treatment and therefore did not increase acute toxicity values. Several by-products generated during TA degradation were identified and possible degradation pathways for the UV-ABC and UV-ABC/H O processes were proposed. |
| ISSN | 00489697 |
| Journal | Science of The Total Environment |
| Volume Number | 573 |
| e-ISSN | 18791026 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2016-12-15 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Environmental Chemistry Waste Management and Disposal Pollution Environmental Engineering |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|