NDLI: Electrical detection of single pollen allergen particles using electrode-embedded microchannels.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Noda, Tetsuya Kawai, Tomoji Tsutsui, Makusu Kawano, Satoyuki Kawaguchi, Chihiro Taniguchi, Masateru
Description	Country affiliation: Japan Author Affiliation: Kawaguchi C ( The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, Japan.)
Abstract	We report on the development of a microfluidic system for the electrical detection of single pollen allergen particles. Our device consists of 500 nm electrode gaps fabricated in an 800 nm wide fluidic channel. We flowed pollen allergen particles of average size 330 nm along the channel via fluid pumping and simultaneously monitored temporal change in dc current flowing through the sensing electrodes. Current spikes were detected, which can be attributed to a capacitance discharging upon trapping/detrapping of single allergens in the electrode gap. This sensing mechanism may open new avenues for a highly sensitive pollen allergen sensor.
ISSN	09538984
e-ISSN	1361648X
Journal	Journal of Physics: Condensed Matter
Issue Number	16
Volume Number	24
Language	English
Publisher	IOP Publishing
Publisher Date	2012-04-25
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Allergens Microfluidic Analytical Techniques Instrumentation Pollen Chemistry Cupressus Electrodes Research Support, Non-u.s. Gov't Discipline Condensed Matter Physics
Content Type	Text
Resource Type	Article
Subject	Condensed Matter Physics Materials Science

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Electrical detection of single pollen allergen particles using electrode-embedded microchannels.