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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Lanzi, R. Anchisi, D. Balini, A. Perani, D. Poggi, A. Comi, G. Volonté, M. A. Fazio, F. |
| Description | Country affiliation: Italy Author Affiliation: Volonté MA ( Movement Disorder Unit, Department of Neuroscience, Istituto Scientifico Ospedale San Raffaele, Via Olgettina 60, 20132 Milano, Italy.) |
| Abstract | A [(18)F]-FDG PET study was performed in a 44 year old man with proximal kinesigenic choreoathetosis (PKC) secondary to idiopathic primary hypoparathyroidism (IPH) before and 1 year after calcium/calcitriol therapy. The [(18)F]-FDG PET performed before the start of the therapy disclosed a significant bilateral hypometabolism in the ventral striatum. One year later, with the patient still under calcium/calcitriol therapy and free of any occurrence of PKC episodes, the [(18)F]-FDG PET did not show the previously detected hypometabolism. The hypometabolism of the ventral striatum secondary to hypocalcaemia seems to play a crucial part in the pathogenesis of paroxysmal kinesigenic choreoathetosis associated with IPH. |
| ISSN | 00223050 |
| e-ISSN | 1468330X |
| Journal | Journal of Neurology, Neurosurgery & Psychiatry |
| Issue Number | 5 |
| Volume Number | 71 |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Date | 2001-11-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Basal Ganglia Metabolism Brain Diseases, Metabolic Chemically Induced Calcitriol Adverse Effects Calcium Chorea Drug Therapy Etiology Hypothyroidism Complications Pathology Fluorodeoxyglucose F18 Glucose Magnetic Resonance Imaging Radiopharmaceuticals Tomography, Emission-computed Discipline Neurology Discipline Neurosurgery Discipline Psychiatry |
| Content Type | Text |
| Resource Type | Article Case study |
| Subject | Neurology (clinical) Surgery Psychiatry and Mental Health |
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