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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Yang, Xiao-Hong Liu, Jin-Ku Wang, Jian-Dong Lu, Yi Jiang, Hao Hong, Dan-Jing Zhang, Min |
| Description | Author Affiliation: Jiang H ( Key Laboratory for Advanced Materials, East China University of Science and Technology, Shanghai 200237 PR China.); Liu JK ( Key Laboratory for Advanced Materials, East China University of Science and Technology, Shanghai 200237 PR China. Electronic address: jkliu@ecust.edu.cn.); Wang JD ( Key Laboratory for Advanced Materials, East China University of Science and Technology, Shanghai 200237 PR China.); Lu Y ( Key Laboratory for Advanced Materials, East China University of Science and Technology, Shanghai 200237 PR China.); Zhang M ( Key Laboratory for Advanced Materials, East China University of Science and Technology, Shanghai 200237 PR China.); Yang XH ( Department of Chemistry, Chizhou University, Chizhou 247000, PR China. Electronic address: yxh6110@yeah.net.); Hong DJ ( Key Laboratory for Advanced Materials, East China University of Science and Technology, Shanghai 200237 PR China.) |
| Abstract | In the present study, hydroxyapatite (HAP) nanoparticles of different particle sizes with high crystallinity and similiar structure were prepared by hydrothermal method. The crystal structure and particle size were characterized by X-ray diffraction pattern (XRD), transmission electron microscopy (TEM) and Fourier transform infrared (FT-IR) spectroscopy. Mung bean sprouts were first used as experimental models. Instead of by MTT assay, the cytoxicity of HAP nanoparticles were proved and evaluated by measuring the hypocotyle length of mung bean sprouts in the culture media. The result showed that the inhibition effect to the growth of mung bean sprouts enhanced when HAP nanoparticles existed. Culture media of HAP nanoparticles with different concentrations and particle sizes was prepared to investigate the level of inhibition effect to the growth of mung bean sprouts. The result found that hypocotyl length of mung bean sprouts were the shortest cultured in 5mg/mL culture media in which the HAP nanoparticles were prepared by hydrothermal method for 24h. It was concluded the inhibition effect depended on the amount of intracellular HAP nanoparticles. The nanostructure and Ca(2+) concentration were considered as the main factors to cause cell apoptosis which was the reason of inhibition. The study provided a preliminary perspective about biotoxicity of HAP nanomaterials to the plant growth. |
| ISSN | 03043894 |
| Volume Number | 270 |
| e-ISSN | 18733336 |
| Journal | Journal of Hazardous Materials |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-04-15 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Durapatite Toxicity Fabaceae Drug Effects Nanoparticles Apoptosis Chemistry Growth & Development Ultrastructure Microscopy, Electron, Transmission Particle Size Seedling Spectroscopy, Fourier Transform Infrared X-ray Diffraction Journal Article Research Support, Non-u.s. Gov't Discipline Environmental Science Discipline Environmental Chemistry |
| Content Type | Text |
| Resource Type | Article |
| Subject | Environmental Chemistry Pollution Waste Management and Disposal Health, Toxicology and Mutagenesis Environmental Engineering |
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