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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Du, Xin He, Junhui |
| Description | Country affiliation: China Author Affiliation: Du X ( Functional Nanomaterials Laboratory and Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences (CAS), Zhongguancun Beiyitiao 2, Haidianqu, Beijing 100190, China.) |
| Abstract | In this work, in situ encapsulation of ibuprofen (IBU) was explored preliminarily using the emulsion sol-gel method. IBU-containing porous silica nanospheres (300-400 nm) of varied morphologies were fabricated simply by tailoring the amount of IBU in the starting solution. In the reaction system, IBU exists in the form of IBU(-) under basic conditions, which has strong electrostatic interaction with CTA(+), and thus could be regarded as cosurfactant to regulate the morphology and structure of silica nanospheres. Such morphology can be maintained even after calcination or IBU release in phosphate-buffered saline. The current results may shed light on the design and construction of new functional nanoarchitectures, which may be useful for drug delivery, separation, adsorption, catalysis, etc. |
| ISSN | 00219797 |
| Issue Number | 2 |
| Volume Number | 345 |
| e-ISSN | 10957103 |
| Journal | Journal of Colloid and Interface Science |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2010-05-15 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Anti-inflammatory Agents, Non-steroidal Chemistry Drug Carriers Ibuprofen Nanospheres Silicon Dioxide Delayed-action Preparations Porosity Static Electricity Journal Article Research Support, Non-u.s. Gov't Discipline Colloid & Interface Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Surfaces, Coatings and Films Colloid and Surface Chemistry Biomaterials Electronic, Optical and Magnetic Materials |
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