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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Van Den Berg, Harold H. J. L. Lodder-Verschoor, Froukje Lodder, Willemijn J. Duizer, Erwin Koopmans, Marion Rutjes, Saskia A. de Roda Husman, Ana Maria Vennema, Harry |
| Spatial Coverage | Netherlands |
| Description | Country affiliation: Netherlands Author Affiliation: Rutjes SA ( Laboratory for Zoonoses and Environmental Microbiology, Centre for Infectious Disease Control Netherlands, National Institute for Public Health and the Environment, Bilthoven, The Netherlands. saskia.rutjes@rivm.nl) |
| Abstract | Non-travel-related hepatitis E virus (HEV) genotype 3 infections in persons in the Netherlands may have a zoonotic, foodborne, or water-borne origin. Possible reservoirs for HEV transmission by water, food, and animals were studied. HEV genotype 3/open reading frame 2 sequences were detected in 53% of pig farms, 4% of wild boar feces, and 17% of surface water samples. HEV sequences grouped within 4 genotype 3 clusters, of which 1 is so far unique to the Netherlands. The 2 largest clusters contained 35% and 43% of the animal and environmental sequences and 75% and 6%, respectively, of human HEV sequences obtained from a study on Dutch hepatitis E patients. This finding suggests that infection risk may be also dependent on transmission routes other than the ones currently studied. Besides the route of exposure, virus characteristics may be an important determinant for HEV disease in humans. |
| ISSN | 10806040 |
| e-ISSN | 10806059 |
| DOI | 10.3201/eid1503.071472 |
| Journal | Emerging Infectious Diseases |
| Issue Number | 3 |
| Volume Number | 15 |
| Language | English |
| Publisher | Centers for Disease Control and Prevention |
| Publisher Date | 2009-03-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Arvicolinae Virology Hepatitis E Virus Hepatitis E Transmission Sus Scrofa Swine Zoonoses Animal Husbandry Animals Feces Food Microbiology Genotype Epidemiology Classification Genetics Isolation & Purification Netherlands Rodent Diseases Swine Diseases Research Support, Non-u.s. Gov't Discipline Infectious Diseases |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Epidemiology Microbiology (medical) |
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