NDLI: Survival during renal replacement therapy among African Americans infected with HIV type 1 in urban Baltimore, Maryland.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Mehta, Shruti H. Atta, Mohamed G. Moore, Richard D. Fine, Derek M. Kirk, Gregory D. Lucas, Gregory M.
Spatial Coverage	Baltimore
Description	Country affiliation: United States Author Affiliation: Atta MG ( Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. matta1@jhmi.edu)
Abstract	BACKGROUND: African Americans with human immunodeficiency virus type 1 (HIV-1) infection and kidney disease are at increased risk of end-stage renal disease requiring renal replacement therapy (RRT), particularly in urban areas with high rates of poverty and injection drug use. It is unknown how the widespread use of highly active antiretroviral therapy (HAART) has affected survival during RRT in this vulnerable population. METHODS: African American patients infected with HIV-1 who required RRT were identified from 2 cohorts that included 4509 Africans Americans infected with HIV-1 who were recruited during the period 1988-2004 in Baltimore, Maryland. Survival after initiation of RRT was compared for those who initiated treatment in the pre-HAART and the HAART eras using Kaplan-Meier curves. Cox proportional hazards regression analysis was used to adjust for potential confounders. RESULTS: RRT was initiated in 162 patients (3.6%) during 10.6 years of follow-up (119 during the HAART era). Compared with patients who started RRT in the pre-HAART era, those in the HAART era were older (P<.001) and more likely to have CD4 cell counts of
ISSN	10584838
e-ISSN	15376591
DOI	10.1086/523728
Journal	Clinical Infectious Diseases
Issue Number	12
Volume Number	45
Language	English
Publisher	Oxford University Press
Publisher Date	2007-12-15
Publisher Place	United States
Access Restriction	Open
Subject Keyword	African Americans Antiretroviral Therapy, Highly Active Hiv Infections Ethnology Hiv-1 Kidney Failure, Chronic Renal Replacement Therapy Mortality Baltimore Cohort Studies Complications Therapy Research Support, N.i.h., Extramural Discipline Infectious Diseases
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Microbiology (medical)

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