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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Li, He Wei, Qin Yan, Liangguo Ma, Hongmin Du, Bin Yu, Shujun Wu, Dan Zhang, Yong |
| Description | Author Affiliation: Yu S ( Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, PR China.) |
| Abstract | A highly sensitive label-free immunosensor for the detection of kanamycin had been developed using silver hybridized mesoporous ferroferric oxide nanoparticles (Ag@Fe3O4 NPs) and thionine mixed graphene sheet (TH-GS). TH was used as an electron transfer mediator. The electrical signal was greatly improved in the presence of GS due to its good electron-transfer ability. With the advantages of large specific surface area and excellent electrical conductivity, Ag@Fe3O4 NPs could immobilize more antibodies of kanamycin and promote the electron transfer. Cyclic voltammetry and square wave voltammetry were used to characterize the recognition of kanamycin. The proposed immunosensor showed good performances such as low detection limit (15 pg mLâ »¹), wide linear range (from 0.050 to 16 ng mLâ »¹), short analysis time (3 min), high stability, and good selectivity in the detection of kanamycin. The immunosensor was evaluated for pork meat sample, receiving satisfactory results. |
| ISSN | 09565663 |
| Volume Number | 48 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-10-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Anti-bacterial Agents Analysis Graphite Chemistry Kanamycin Nanoparticles Phenothiazines Silver Animals Antibodies, Immobilized Biosensing Techniques Methods Electrochemical Techniques Ferrosoferric Oxide Limit Of Detection Meat Swine Evaluation Studies Journal Article Research Support, Non-u.s. Gov't Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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