NDLI: Bioprocess development for the production of sonorensin by Bacillus sonorensis MT93 and its application as a food preservative.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Chopra, Lipsy Sahoo, Debendra K. Singh, Gurdeep Jena, Kautilya Kumar Verma, Himanshu
Description	Country affiliation: India Author Affiliation: Chopra L ( Biochemical Engineering Research and Process Development Centre, CSIR-Institute of Microbial Technology, Sector-39A, Chandigarh 160036, India.); Singh G ( Biochemical Engineering Research and Process Development Centre, CSIR-Institute of Microbial Technology, Sector-39A, Chandigarh 160036, India.); Jena KK ( Biochemical Engineering Research and Process Development Centre, CSIR-Institute of Microbial Technology, Sector-39A, Chandigarh 160036, India.); Verma H ( Biochemical Engineering Research and Process Development Centre, CSIR-Institute of Microbial Technology, Sector-39A, Chandigarh 160036, India.); Sahoo DK ( Biochemical Engineering Research and Process Development Centre, CSIR-Institute of Microbial Technology, Sector-39A, Chandigarh 160036, India. Electronic address: debsahoo@imtech.res.in.)
Abstract	Media composition and environmental conditions were optimized using statistical tools, Plackett Burman design and response surface methodology, to maximize the yield of a bacteriocin, named as sonorensin, from a new marine isolate Bacillus sonorensis MT93 showing broad spectrum of antimicrobial activity. Under optimized conditions, MT93 produced 15-fold higher yield of sonorensin compared to that under initial fermentation conditions. As oxygen supply is a critical parameter controlling growth and product formation in aerobic bioprocesses and used as a parameter for bioprocess scale up, the effects of oxygen transfer, in terms of volumetric oxygen transfer coefficient (kLa), on production of sonorensin was investigated using optimized medium composition in a bioreactor. Studies on effectiveness of sonorensin against Staphylococcus aureus and Listeria monocytogenes in fruit juice and as a preservative in pasteurized milk demonstrated its potential as a biopreservative in fruit products and shelf life extender of the pasteurized milk.
ISSN	09608524
Journal	Bioresource Technology
Volume Number	175
e-ISSN	18732976
Language	English
Publisher	Elsevier
Publisher Date	2015-01-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Bioresource
Content Type	Text
Resource Type	Article
Subject	Waste Management and Disposal Medicine Environmental Engineering Renewable Energy, Sustainability and the Environment Bioengineering

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