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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Burgueño, Joan F. Bosser, Ramon Kosoy, Ana Seras-Franzoso, Joaquin Villaverde, Antonio Mendoza, Rosa Ruiz-Avila, Luis Corchero, José L. Vázquez, Esther Fernández, Ester Martínez-Láinez, Joan Marc García-Fruitós, Elena Rinas, Ursula |
| Description | Country affiliation: Spain Author Affiliation: Vázquez E ( Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.) |
| Abstract | Inclusion bodies (50-500 nm in diameter) produced in recombinant bacteria can be engineered to contain functional proteins with therapeutic potential. Upon exposure, these protein particles are efficiently internalized by mammalian cells and promote recovery from diverse stresses. Being fully biocompatible, inclusion bodies are a novel platform, as tailored nanopills, for sustained drug release in advanced cell therapies. |
| ISSN | 09359648 |
| Issue Number | 13 |
| Volume Number | 24 |
| e-ISSN | 15214095 |
| Journal | Advanced Materials |
| Language | English |
| Publisher | Wiley-VCH |
| Publisher Date | 2012-04-03 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Delayed-action Preparations Metabolism Escherichia Coli Inclusion Bodies Recombinant Proteins Administration & Dosage Animals Catalase Therapeutic Use Cell Line Cell Membrane Permeability Green Fluorescent Proteins Hsp70 Heat-shock Proteins Hela Cells Humans Leukemia Inhibitory Factor Mice Tetrahydrofolate Dehydrogenase Journal Article Research Support, Non-u.s. Gov't Discipline Materials Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Mechanics of Materials Mechanical Engineering |
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