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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Li, Na Zhang, Donna D. Wong, Pak Kin Wang, Shue Riahi, Reza |
| Description | Country affiliation: United States Author Affiliation: Wang S ( Department of Aerospace and Mechanical Engineering, The University of Arizona, Tucson, AZ, 85721, USA.); Riahi R ( Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology and Harvard Medical School, Cambridge, MA, 02139, USA.); Li N ( Department of Mechanical and Aerospace Engineering, University of Miami, Coral Gables, FL, 33146, USA.); Zhang DD ( Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ, 85724, USA.); Wong PK ( Department of Aerospace and Mechanical Engineering, The University of Arizona, Tucson, AZ, 85721, USA.) |
| Abstract | A gold nanorod-locked nucleic acid nano-biosensor for dynamic single-cell gene expression analysis in living cells and tissues is developed. The nanoparticle facilitates endocytic delivery and dynamic monitoring of the gene expression in human umbilical cord endothelial cells, mouse skin tissues, mouse retina tissues, and mouse cornea tissues at the single-cell level. |
| ISSN | 09359648 |
| Issue Number | 39 |
| Volume Number | 27 |
| e-ISSN | 15214095 |
| Journal | Advanced Materials |
| Language | English |
| Publisher | Wiley-VCH |
| Publisher Date | 2015-10-21 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Biosensing Techniques Gene Expression Profiling Instrumentation Gold Metal Nanoparticles Nanotubes Animals Cells, Cultured Cornea Cytology Metabolism Cytoplasm Endothelial Cells Fetal Blood Gene Expression Methods Chemistry Humans Mice, Inbred C57bl Nucleic Acid Probes Particle Size Rna, Messenger Retina Single-cell Analysis Stem Cells Journal Article Research Support, N.i.h., Extramural Discipline Materials Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Mechanics of Materials Mechanical Engineering |
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