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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Tennyson, V. M. |
| Abstract | The centrally directed neurite of the dorsal root neuroblast has been described from the period of its initial entrance into the neural tube until a well-defined dorsal root is formed. Large numbers of microtubules, channels of agranular reticulum, and clusters of ribosomes are found throughout the length of the early axons. The filopodia of the growth cone appear as long thin processes or as broad flanges of cytoplasm having a finely filamentous matrix material and occasionally small ovoid or elongate vesicles. At first the varicosity is a small expansion of cytoplasm, usually containing channels of agranular reticulum and a few other organelles. The widely dilated cisternae of agranular reticulum frequently found within the growth cone probably correspond to the pinocytotic vacuoles seen in neurites in tissue culture. The varicosities enlarge to form bulbous masses of cytoplasm, which may measure up to 5 micro in width and 13 micro in length. They contain channels of agranular reticulum, microtubules, neurofilaments, mitochondria, heterogeneous dense bodies, and a few clusters of ribosomes. Large ovoid mitochondria having ribonucleoprotein particles in their matrix are common. Dense membrane specializations are found at the basal surface of the neuro-epithelial cell close to the area where the early neurites first enter the neural tube. |
| ISSN | 00219525 |
| e-ISSN | 15408140 |
| Journal | The Journal of Cell Biology |
| Issue Number | 1 |
| Volume Number | 44 |
| Language | English |
| Publisher | Rockefeller University Press (United States) |
| Publisher Date | 1970-01-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Axons Cytology Ganglia, Spinal Embryology Animals Culture Techniques Cytoplasmic Granules Endoplasmic Reticulum Gestational Age Membranes Microscopy, Electron Mitochondria Neurofibrils RNA Rabbits Ribosomes Cell Biology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Medicine |
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