NDLI: One-Step Synthesis of Racemic α-Amino Acids from Aldehydes, Amine Components, and Gaseous $CO_{2}$ by the Aid of a Bismetal Reagent

Please wait, while we are loading the content...

Year: 2017 Volume: 23

Year: 2016 Volume: 22

Year: 2015 Volume: 21

Year: 2014 Volume: 20

Year: 2013 Volume: 19

Year: 2013 Volume: 19 Issue: 52

Year: 2013 Volume: 19 Issue: 51

Year: 2013 Volume: 19 Issue: 50

Year: 2013 Volume: 19 Issue: 49

Year: 2013 Volume: 19 Issue: 48

Year: 2013 Volume: 19 Issue: 47

Year: 2013 Volume: 19 Issue: 46

Year: 2013 Volume: 19 Issue: 45

Year: 2013 Volume: 19 Issue: 44

Year: 2013 Volume: 19 Issue: 43

Year: 2013 Volume: 19 Issue: 42

Year: 2013 Volume: 19 Issue: 41

Year: 2013 Volume: 19 Issue: 40

Year: 2013 Volume: 19 Issue: 39

Year: 2013 Volume: 19 Issue: 38

Year: 2013 Volume: 19 Issue: 37

Year: 2013 Volume: 19 Issue: 36

Year: 2013 Volume: 19 Issue: 35

Year: 2013 Volume: 19 Issue: 34

Year: 2013 Volume: 19 Issue: 33

Year: 2013 Volume: 19 Issue: 32

Year: 2013 Volume: 19 Issue: 31

Year: 2013 Volume: 19 Issue: 30

Year: 2013 Volume: 19 Issue: 29

Year: 2013 Volume: 19 Issue: 28

Year: 2013 Volume: 19 Issue: 27

Year: 2013 Volume: 19 Issue: 26

Year: 2013 Volume: 19 Issue: 25

Year: 2013 Volume: 19 Issue: 24

Year: 2013 Volume: 19 Issue: 23

Year: 2013 Volume: 19 Issue: 22

Year: 2013 Volume: 19 Issue: 21

Year: 2013 Volume: 19 Issue: 20

Year: 2013 Volume: 19 Issue: 19

Year: 2013 Volume: 19 Issue: 18

Year: 2013 Volume: 19 Issue: 17

Year: 2013 Volume: 19 Issue: 16

Year: 2013 Volume: 19 Issue: 15

Year: 2013 Volume: 19 Issue: 14

Year: 2013 Volume: 19 Issue: 13

Year: 2013 Volume: 19 Issue: 12

Year: 2013 Volume: 19 Issue: 11

Year: 2013 Volume: 19 Issue: 10

Year: 2013 Volume: 19 Issue: 9

Year: 2013 Volume: 19 Issue: 8

Year: 2013 Volume: 19 Issue: 7

Year: 2013 Volume: 19 Issue: 6

Year: 2013 Volume: 19 Issue: 5

Year: 2013 Volume: 19 Issue: 4

Year: 2013 Volume: 19 Issue: 3

Synthesis of Imides by Palladium-Catalyzed CH Functionalization of Aldehydes with Secondary Amides

Site-Specific Labeling of Proteins with a Chemically Stable, High-Affinity Tag for Protein Study

Thiol-Directed Synthesis of Highly Fluorescent Gold Clusters and Their Conversion into Stable Imaging Nanoprobes

Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes

Copper(I) and Silver(I) Bis(trifluoromethanesulfonyl)imide and Their Interaction with an Arene, Diverse Olefins, and an $NTf_{2}^{−}-Based$ Ionic Liquid

Highly Stable Amorphous Calcium Phosphate Porous Nanospheres: Microwave-Assisted Rapid Synthesis Using ATP as Phosphorus Source and Stabilizer, and Their Application in Anticancer Drug Delivery

$Fe^{III}$ Quinolylsalicylaldimine Complexes: A Rare Mixed-Spin-State Complex and Abrupt Spin Crossover

Rapid, General Synthesis of PdPt Bimetallic Alloy Nanosponges and Their Enhanced Catalytic Performance for Ethanol/Methanol Electrooxidation in an Alkaline Medium

Encapsulating Sulfur into Hierarchically Ordered Porous Carbon as a High-Performance Cathode for Lithium–Sulfur Batteries

Tuning the Nature of the Fluorescent State: A Substituted Polycondensed Dye as a Case Study

Low Catalyst Loading in Ring-Closing Metathesis Reactions

Selective Dimerization of Lewis-Acid/Base-Stabilized Phosphanylalanes

Preparation of a Hyper-cross-linked Polymer Monolithic Column and Its Application to the Sensitive Determination of Genomic DNA Methylation

Expanding the Applications of the Ilmenite Mineral to the Preparation of Nanostructures: $TiO_{2}$ Nanorods and their Photocatalytic Properties in the Degradation of Oxalic Acid

Origin of the Magnetic Anisotropy in Heptacoordinate $Ni^{II}$ and $Co^{II}$ Complexes

One-Step Synthesis of Racemic α-Amino Acids from Aldehydes, Amine Components, and Gaseous $CO_{2}$ by the Aid of a Bismetal Reagent

Small Changes Have Consequences: Lessons from Tetrabenzyltitanium and -zirconium Surface Organometallic Chemistry

Construction of Supramolecular Self-Assembled Microfibers with Fluorescent Properties through a Modified Ionic Self-Assembly (ISA) Strategy

Chiral Triazolium Salts and Ionic Liquids: From the Molecular Design Vectors to Their Physical Properties through Specific Supramolecular Interactions

Relating the Composition of $Pt_{x}Ru_{100−x}/C$ Nanoparticles to Their Structural Aspects and Electrocatalytic Activities in the Methanol Oxidation Reaction

Aggregation Effects in Visible-Light Flavin Photocatalysts: Synthesis, Structure, and Catalytic Activity of 10-Arylflavins

Magnetic Blocking from Exchange Interactions: Slow Relaxation of the Magnetization and Hysteresis Loop Observed in a Dysprosium–Nitronyl Nitroxide Chain Compound with an Antiferromagnetic Ground State

Improvement of $TiO_{2}/Dye/Electrolyte$ Interface Conditions by Positional Change of Alkyl Chains in Modified Panchromatic Ru Complex Dyes

A PEGylated Fluorescent Turn-On Sensor for Detecting Fluoride Ions in Totally Aqueous Media and Its Imaging in Live Cells

Porous-Organic-Framework-Templated Nitrogen-Rich Porous Carbon as a More Proficient Electrocatalyst than Pt/C for the Electrochemical Reduction of Oxygen

Jozimine $A_{2}:$ The First Dimeric Dioncophyllaceae-Type Naphthylisoquinoline Alkaloid, with Three Chiral Axes and High Antiplasmodial Activity

Rapid Preparation of Mycobacterium N-Glycolyl Lipid I and Lipid II Derivatives: A Biocatalytic Approach

High Intrinsic Barriers against Spin-State Relaxation in Iron(II)-Complex Solutions

Highly Stereoselective Glycosyl-Chloride-Mediated Synthesis of 2-Deoxyglucosides

Ruthenium-Catalyzed Intermolecular Hydroacylation of Internal Alkynes: The Use of Ceria-Supported Catalyst Facilitates the Catalyst Recycling

Radical Addition of Xanthates on Carbon Nanotubes as an Efficient Covalent Functionalization Method

Rhodium-Catalyzed Enantioselective Addition to Unsymmetrical α-Diketones: Tandem One-Pot Synthesis of Optically Active 3-Tetrasubstituted Isochroman Derivatives

Dual Gold Catalysis: σ,π-Propyne Acetylide and Hydroxyl-Bridged Digold Complexes as Easy-To-Prepare and Easy-To-Handle Precatalysts

Preparation of Functionalized Organoindium Reagents by Means of Magnesium Insertion into Organic Halides in the Presence of $InCl_{3}$ at Room Temperature

Mapping the Metal Positions inside Spherical $C_{80}$ Cages: Crystallographic and Theoretical Studies of $Ce_{2}@D_{5h}-C_{80}$ and $Ce_{2}@I_{h}-C_{80}$

$Pd-PEPPSI-IPent^{Cl}:$ An Effective Catalyst for the Preparation of $Triarylamines^{†}$

Solvent-Free, Metal-Free, Aza-Prins Cyclization: Unprecedented Access to δ-Sultams

Mixed Linker Strategies for Organic Framework Functionalization

Boronate Ligands in Materials: Determining Their Local Environment by Using a Combination of IR/Solid-State NMR Spectroscopies and DFT Calculations

Structure of the O-Glycosylated Conopeptide CcTx from Conus consors Venom

Analysis of Potential Molecular Catalysts for the Hydroamination of Ethylene with Ammonia: A DFT Study with [Ir(PCP)] and [Ir(PSiP)] Complexes

Year: 2013 Volume: 19 Issue: 2

Year: 2013 Volume: 19 Issue: 1

Year: 2012 Volume: 18

Year: 2011 Volume: 17

Year: 2010 Volume: 16

Year: 2009 Volume: 15

Year: 2008 Volume: 14

Year: 2007 Volume: 13

Year: 2006 Volume: 12

Year: 2005 Volume: 11

Year: 1997 Volume: 3

One-Step Synthesis of Racemic α-Amino Acids from Aldehydes, Amine Components, and Gaseous $CO_{2}$ by the Aid of a Bismetal Reagent

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Higuchi, Yuki Sato, Yoshihiro Mita, Tsuyoshi
Description	Author Affiliation: Mita T ( Faculty of Pharmaceutical Sciences, Hokkaido University, Nishi 6, Kita 12, Kita-ku, Sapporo 060-0812, Japan. tmita@pharm.hokudai.ac.jp)
Abstract	α-Amino acids are essential resources for human life and are highly useful as building blocks for organic synthesis. The core framework of an α-amino acid can be divided into three basic components: an aldehyde, an amine, and carbon dioxide $(CO_{2}).$ We report herein that a one-step synthesis of α-amino acids has been successfully achieved from these three basic and inexpensive chemicals with a single operation, in which the mixture of an aldehyde, a sulfonamide, and gaseous $CO_{2}$ was heated at 100 °C in the presence of $Bu_{3}Sn-SnBu_{3}$ and CsF. In this one-pot sequential protocol, two important intermediates (imine and α-amino stannane) are involved and the stannyl anion generated in situ plays a crucial role, particularly for the efficient stannylation of the imine in the presence of proton sources and for promoting retrostannylation of the undesired α-alkoxy stannane owing to its high stability and tolerance of the presence of proton sources. This methodology enabled the synthesis of a wide range of racemic arylglycine derivatives in high yields.
ISSN	09476539
e-ISSN	15213765
Journal	Chemistry - A European Journal
Issue Number	3
Volume Number	19
Language	English
Publisher	Wiley-VCH;ChemPubSoc Europe
Publisher Date	2013-01-14
Publisher Place	Germany
Access Restriction	Open
Subject Keyword	Aldehydes Chemistry Amines Amino Acids Chemical Synthesis Carbon Dioxide Organotin Compounds Cesium Fluorides Molecular Structure Stereoisomerism Research Support, Non-U.S. Gov't
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Catalysis

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in