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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Corrêa, José R. Spencer, John D'Angelis do E S Barbosa, Cintya Rodrigues, Marcelo O. Medeiros, Gisele A. Magalhães, Kelly G. Neto, Brenno A. D. Barreto, Gabrielle De Oliveira, Aline L. |
| Description | Author Affiliation: D'Angelis do E S Barbosa C ( LIMA-Laboratório de Inorgânica e Materiais, Campus Universitário Darcy Ribeiro, CEP 70904-970, P.O. Box 4478, Brasilia-DF (Brazil), Also, Graduate Program from DQF-UFPE.) |
| Abstract | Improved cellular selectivity for nucleoli staining was achieved by simple chemical modification of carbon dots (C-dots) synthesized from waste carbon sources such as cow manure (or from glucose). The C-dots were characterized and functionalized (amine-passivated) with ethylenediamine, affording amide bonds that resulted in bright green fluorescence. The new modified C-dots were successfully applied as selective live-cell fluorescence imaging probes with impressive subcellular selectivity and the ability to selectively stain nucleoli in breast cancer cell lineages (MCF-7). The C-dots were also tested in four other cellular models and showed the same cellular selection in live-cell imaging experiments. |
| ISSN | 09476539 |
| e-ISSN | 15213765 |
| Journal | Chemistry - A European Journal |
| Issue Number | 13 |
| Volume Number | 21 |
| Language | English |
| Publisher | Wiley-VCH;ChemPubSoc Europe |
| Publisher Date | 2015-03-23 |
| Publisher Place | Germany |
| Access Restriction | Open |
| Subject Keyword | Chemistry Manure Optical Imaging Animals Quantum Dots Research Support, Non-U.S. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Catalysis |
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