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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ray, J. E. Wade, D. N. Champion, G. D. Day, R. O. |
| Abstract | 1 Non-steroidal anti-inflammatory drugs (NSAID) suppressed compound 48/80-induced histamine release from rat peritoneal cells in vitro in a dose-dependent manner. 2 NSAID suppressed the adenosine triphosphate (ATP) content of rat peritoneal cells in vitro and this correlated strongly with the suppression of compound 48/80-induced histamine release. 3 The correlation demonstrated suggests that the mechanism of action of NSAID in the rat peritoneal cells is via depletion of cellular ATP. |
| ISSN | 00071188 |
| e-ISSN | 14765381 |
| Journal | British Journal of Pharmacology |
| Issue Number | 1 |
| Volume Number | 59 |
| Language | English |
| Publisher | Wiley Online Library(on behalf of The British Pharmacological Society) |
| Publisher Date | 1977-01-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Adenosine Triphosphate Metabolism Anti-Inflammatory Agents Pharmacology Histamine Mast Cells Peritoneum Animals Indomethacin Drug Effects |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pharmacology |
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