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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Narvey, Michael Durst, Michelle A. Wicklow, Brandy |
| Description | Author Affiliation: Durst MA ( University of Manitoba, Department of Paediatrics and Child Health, Winnipeg, Manitoba, Canada.); Wicklow B ( University of Manitoba, Department of Paediatrics and Child Health, Section of Paediatric Endocrinology, Winnipeg, Manitoba, Canada.); Narvey M ( Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.) |
| Abstract | Preterm ovarian hyperstimulation syndrome is a rare syndrome in which preterm infant girls have hypogastric, upper leg and labial swelling accompanied by elevated serum oestradiol levels and ovarian follicular cysts on ultrasound. Our case is an infant born at 23â weeks gestational age who at 30â weeks postconceptional age (PCA) developed elevated 17-hydroxyprogesterone on her newborn screen with associated clitoromegaly and a ventral groove on the inferior aspect of the erectile tissue. An initial pelvic ultrasound at 32â weeks PCA demonstrated a normal appearing uterus, but the ovaries were not visualised. At 39â weeks PCA, follicular ovarian cysts were noted bilaterally (31×26×21â mm on left and 38×25×36â mm on right). Without treatment, oestradiol and testosterone levels began normalising by 42â weeks PCA. After this point, the right ovarian cysts had resolved and the left ovarian cyst continued to diminish in size. |
| Volume Number | 2017 |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Infant, Extremely Premature Ovarian Hyperstimulation Syndrome Blood Complications Virilism Etiology 17-alpha-Hydroxyprogesterone Clitoris Pathology Dehydroepiandrosterone Estradiol Female Humans Infant Infant, Newborn Ovarian Cysts Diagnosis Testosterone Case Reports Journal Article Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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