NDLI: Conformational model of active transport.

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Induction of -aminolevulinic acid synthetase in chick embryo liver cells in cluture.

Conformation and displacement in muscle contraction.

Polyoma 'tumor antigen': an activator of chromosome replication?

DNA synthesis by RNA-containing tumor viruses.

Effect of loss of thymidine kinase activity on the tumorigenicity of clones of SV40-transformed hamster cells.

Coboglobins: oxygen-carrying cobalt-reconstituted hemoglobin and myoglobin.

Cyclic adenosine 3':5'-monophosphate-stimulated phosphorylation of isolated neurotubule subunits.

Increase in preexisting cellular antigen-combining groups at different times after infection with different viruses.

Enzymatic block in the synthesis of gangliosides in DNA virus-transformed tumorigenic mouse cell lines.

Correlation of adrenocorticotropic activity of ACTH analogs with degree of binding to an adrenal cortical particulate preparation.

Isolation of a second avian leukosis group-specific antigen (gs-b) from avian myeloblastosis virus.

Evidence for a DNA replicative genome for RNA-containing tumor viruses.

Elevated concentration of adenosine 3':5'-cyclic monophosphate in intestinal mucosa after treatment with cholera toxin.

A possible role of phospholipid in nerve excitation.

Absence of a cell membrane alteration function in non-transforming mutants of polyoma virus.

Reciprocal hunger-regulating circuits involving alpha- and beta-adrenergic receptors located, respectively, in the ventromedial and lateral hypothalamus.

Dopamine as a synaptic transmitter and modulator in sympathetic ganglia: a different mode of synaptic action.

Purification of a specific tRNA by Sepharose-bound enzyme.

Non-chromosomal antibiotic resistance in bacteria. 3. Isolation of the discrete transfer unit of the R-factor R1.

Immunogenicity of Mycoplasma pneumoniae glycolipids: a novel approach to the production of antisera to membrane lipids.

A density label for membranes.

Correlation of in vivo and in vitro phase transitions of membrane lipids in Escherichia coli.

DNA replication in Escherichia coli: location of recently incorporated thymidine within molecules of high molecular weight DNA.

A Saccharomyces cerevisiae mutant defective in saturated fatty acid biosynthesis.

Replication and repair of DNA in cells of Escherichia coli treated with toluene.

A specific hepatic transfer RNA for phosphoserine.

The selective inhibition of protein initiation by T4 phage-induced factors.

On the process of cellular division in Escherichia coli. V. Incorporation of deoxynucleoside triphosphates by DNA thermosensitive mutants of Escherichia coli also lacking DNA polymerase activity.

A DNA-acrylamide gel column for analyzing proteins that bind to DNA. I. DNA polymerase.

A lesson from the smog capital of the world.

In vitro biosynthesis of pseudouridine at the polynucleotide level by an enzyme extract from Escherichia coli.

Chromosomal distribution of rapidly reannealing DNA in Drosophila melanogaster.

Role of Phosphorylation Coupling Factor in Light-Dependent Proton Translocation by Rhodopseudomonas capsulata Membrane Preparations

Symmetric replication of the Bacillus subtilis chromosome.

Temperature-sensitive mutations in Drosophila melanogaster. IV. A mutation affecting eye facet arrangement in a polarized manner.

The relationship of African apes, man and old world monkeys.

Mutations altering chloroplast ribosome phenotype in Chlamydomonas. I. Non-mendelian mutations.

Isolation of -L-glutaminyl 4-hydroxybenzene and -L-glutaminyl 3,4-benzoquinone: a natural sulfhydryl reagent, from sporulating gill tissue of the mushroom Agaricus bisporus.

Mechanism of Thyroid Calorigenesis: Role of Active Sodium Transport

Phenyldiimide, hemoglobin, and Heinz bodies.

Optical activity of bovine neurophysins and their peptide complexes in the near ultraviolet.

Progesterone 'receptors' in the cytoplasm and nucleus of chick oviduct target tissue.

A factor for the binding of aminoacyl transfer RNA to mammalian 40S ribosomal subunits.

Peptide chain termination: effect of protein S on ribosomal binding of release factors.

The conformational basis of energy transductions in biological systems.

Conformational model of active transport.

Fluorescent probe environment and the structural and charge changes in energy coupling of mitochondrial membranes.

Fluorescent probes of biological membranes.

Isogeneic lymphocyte interaction: recognition of self antigens by cells of the neonatal thymus.

Interferon: evidence for subunit structure.

Isolation of RNA with properties of messenger RNA from cerebral polyribosomes.

Proton magnetic resonance studies of Chromatium high-potential iron protein.

Ion transport underlying metabolically controlled volume changes of isolated mitochondria.

Messenger characteristics of nascent bacteriophage RNA.

Bovine liver glutamate dehydrogenase: tentative amino acid sequence; identification of a reactive lysine; nitration of a specific tyrosine and loss of allosteric inhibition by guanosine triphosphate.

Serological and Immunogenic Activity of Soluble Mouse Transplantation Antigens Controlled by the H-2 Locus

Glucocorticoid inhibition of RNA synthesis responsible for cleft palate in mice: a model.

Regulation of acetylcholinesterase in neuroblastoma cells.

Total suppression of pregnancy in mice by post-coital administration of neuraminidase.

Kinetic model of conduction changes across excitable membranes.

Wiskott-Aldrich syndrome, a genetically determined cellular immunologic deficiency: clinical and laboratory responses to therapy with transfer factor.

The use of standards in achieving appropriate levels of tolerance.

Carbon dioxide and its role in climate change.

The global food supply.

Evaluation of the effects of chemical mutagens on man: the long road ahead.

The nucleotide sequence at the 5'-terminus of the Q RNA minus trand.

Phonoangiography: a new noninvasive diagnostic method for studying arterial disease.

Mechanism of polymerization of the Salmonella O-antigen: utilization of lipid-linked intermediates.

Two radiation-induced chromosomal inversions in mice (Mus musculus).

Sites of synthesis and processing of ribosomal RNA presurosrs within the nucleolus of Urechis caupo eggs.

Interallelic complementation in hybrid cells derived from human diploid strains deficient in galactose-1-phosphate uridyl transferase activity.

Differentiation of Mouse Plasmocytomas In Vitro: Two Phenotypically Stabilized Variants of the Same Cell

Tissue localization of lymphocytes bearing a membrane receptor for antigen-antibody-complement complexes.

Chloride and Potassium Activities in Luminal Fluid of Turtle Thyroid Follicles as Determined by Selective Ion-Exchanger Microelectrodes

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Conformational model of active transport.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Green, D. E. Vanderkooi, G. Young, J. H. Blondin, G. A.
Abstract	A model of active transport of monovalent cations in mitochondria is developed. The model is based on the coupling of electron transfer to the generation of a metastable protein conformation which in turn leads to the generation of an asymmetric surface charge, a membrane potential, and a redistribution of diffusible ions across the inner mitochondrial membrane. The ions at all times move spontaneously down an electrochemical potential gradient in this model so that there is no need to invoke the concept of an ion pump. It is shown that a wide variety of experimental facts can be rationalized in terms of the present model.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	2
Volume Number	67
Language	English
Publisher	National Academy of Sciences
Publisher Date	1970-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Biological Transport, Active Energy Transfer Mitochondria Metabolism Protein Conformation Adenosine Triphosphate Cell Membrane Permeability Drug Effects Chlorides Hydrolysis Membrane Potentials Models, Chemical Models, Structural Phosphates Potassium Rubidium Valinomycin Pharmacology Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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