NDLI: Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1989 Volume: 86 Issue: 24

Year: 1989 Volume: 86 Issue: 23

Year: 1989 Volume: 86 Issue: 22

Year: 1989 Volume: 86 Issue: 21

Year: 1989 Volume: 86 Issue: 20

Year: 1989 Volume: 86 Issue: 19

Year: 1989 Volume: 86 Issue: 18

Year: 1989 Volume: 86 Issue: 17

Year: 1989 Volume: 86 Issue: 16

Year: 1989 Volume: 86 Issue: 15

Year: 1989 Volume: 86 Issue: 14

Year: 1989 Volume: 86 Issue: 13

Year: 1989 Volume: 86 Issue: 12

Year: 1989 Volume: 86 Issue: 11

Year: 1989 Volume: 86 Issue: 10

Year: 1989 Volume: 86 Issue: 9

Isolation and structural characterization of cDNA clones encoding the mating pheromone Er-1 secreted by the ciliate Euplotes raikovi.

T-cell interleukin 1 receptor cDNA expressed in Chinese hamster ovary cells regulates functional responses to interleukin 1.

Identification of amino acid residues essential for the enzymatic activities of pertussis toxin.

Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.

Linker insertion mutagenesis of the human immunodeficiency virus reverse transcriptase expressed in bacteria: definition of the minimal polymerase domain.

A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets.

High initiation rates at the ribosomal gene promoter do not depend upon spacer transcription.

Experimental approaches to hypothetical hormones: detection of a candidate ligand of the neu protooncogene.

Transfection of fetal rat intestinal epithelial cells by viral oncogenes: establishment and characterization of the E1A-immortalized SLC-11 cell line.

Tyrosine phosphorylation of the insulin receptor is not required for receptor internalization: studies in 2,4-dinitrophenol-treated cells.

Differential use of termination codons in ciliated protozoa.

Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

Selective replication of simian immunodeficiency virus in a subset of CD4+ lymphocytes.

Physical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodies.

Two genetically identical antigen-presenting cell clones display heterogeneity in antigen processing.

Unique properties of non-N-methyl-D-aspartate excitatory responses in cultured purkinje neurons.

Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.

Decreased susceptibility of a 70-kDa protein to cathepsin L after phosphorylation by protein kinase C.

Mechanism of mercury(II) reductase and influence of ligation on the reduction of mercury(II) by a water soluble 1,5-dihydroflavin.

Structure and function of the Zn(II) binding site within the DNA-binding domain of the GAL4 transcription factor.

Developmental control of lymphokine gene expression in fetal thymocytes during T-cell ontogeny.

Microvascular sites and characteristics of sickle cell adhesion to vascular endothelium in shear flow conditions: pathophysiological implications.

Recombinant growth hormone enhances muscle myosin heavy-chain mRNA accumulation and amino acid accrual in humans.

Role of endothelium-derived nitric oxide in the regulation of blood pressure.

Integration of mini-retroviral DNA: a cell-free reaction for biochemical analysis of retroviral integration.

Proofreading by the epsilon subunit of Escherichia coli DNA polymerase III increases the fidelity of calf thymus DNA polymerase alpha.

Atriopeptin inhibition of thrombin-mediated changes in the morphology and permeability of endothelial monolayers.

Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors.

Regulation of the function of eukaryotic DNA topoisomerase I: topological conditions for inactivity.

Antibodies specific to the retinoic acid human nuclear receptors alpha and beta.

The virD operon of Agrobacterium tumefaciens Ti plasmid encodes a DNA-relaxing enzyme.

Molecular cloning of plant transcripts encoding protein kinase homologs.

Basic fibroblast growth factor is a substrate for protein phosphorylation and is phosphorylated by capillary endothelial cells in culture.

Heparin suppresses the induction of c-fos and c-myc mRNA in murine fibroblasts by selective inhibition of a protein kinase C-dependent pathway.

Heterologous desensitization of bombesin-induced mitogenesis by prolonged exposure to vasopressin: a post-receptor signal transduction block.

denV gene of bacteriophage T4 restores DNA excision repair to mei-9 and mus201 mutants of Drosophila melanogaster.

The Tc2 transposon in Caenorhabditis elegans.

Successive steps in the process of immortalization identified by transfer of separate bovine papillomavirus genes into rat fibroblasts.

Exonuclease III and the catalase hydroperoxidase II in Escherichia coli are both regulated by the katF gene product.

Reversible sodium pump defect and swelling in the diabetic rat erythrocyte: effects on filterability and implications for microangiopathy.

Molecular cloning and expression of cDNA for a carcinoembryonic antigen-related fetal liver glycoprotein.

Antibodies to CD4 in individuals infected with human immunodeficiency virus type 1.

Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector.

Decreased messenger RNA translation in herpesvirus-infected arterial cells: effects on cholesteryl ester hydrolase.

An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines.

Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.

Angiotensin II induces oscillations of intracellular calcium and blocks anomalous inward rectifying potassium current in mouse renal juxtaglomerular cells.

Lipoxin A4 antagonizes cellular and in vivo actions of leukotriene D4 in rat glomerular mesangial cells: evidence for competition at a common receptor.

Regulation of the gastrin promoter by epidermal growth factor and neuropeptides.

Changes in stability and allosteric properties of aspartate transcarbamoylase resulting from amino acid substitutions in the zinc-binding domain of the regulatory chains.

Inhibition of insulin receptor phosphorylation by peptides derived from major histocompatibility complex class I antigens.

Gene for proliferating-cell nuclear antigen (DNA polymerase delta auxiliary protein) is present in both mammalian and higher plant genomes.

Tumor-specific loss of 11p15.5 alleles in del11p13 Wilms tumor and in familial adrenocortical carcinoma.

Virus-induced delayed-type hypersensitivity reaction is sequentially mediated by CD8+ and CD4+ T lymphocytes.

Specific interaction of aurintricarboxylic acid with the human immunodeficiency virus/CD4 cell receptor.

Co-release of acetylcholine and gamma-aminobutyric acid by a retinal neuron.

Single potassium channels opened by opioids in rat locus ceruleus neurons.

A host-encoded DNA-binding protein promotes termination of plasmid replication at a sequence-specific replication terminus.

A hydrogenase-linked gene in Methanobacterium thermoautotrophicum strain delta H encodes a polyferredoxin.

Protein fragments as probes in the study of protein folding mechanisms: differential effects of dihydrofolate reductase fragments on the refolding of the intact protein.

Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse.

Evidence for several higher order structural elements in ribosomal RNA.

Rat amylin: cloning and tissue-specific expression in pancreatic islets.

Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes.

Intron and upstream sequences regulate expression of the Drosophila beta 3-tubulin gene in the visceral and somatic musculature, respectively.

A plant manganese superoxide dismutase is efficiently imported and correctly processed by yeast mitochondria.

T-cell mitogenesis stimulates the synthesis of a mRNA species coding for a 43-kDa peptide reactive with CM-H-9, a monoclonal antibody specific for placental isoferritin.

Identification and characterization of a membrane-bound cytotoxin of murine cytolytic lymphocytes that is related to tumor necrosis factor/cachectin.

Long-term observations of autoimmune-prone mice treated for autoimmune disease by allogeneic bone marrow transplantation.

Immunocytochemical localization of beta II subspecies of protein kinase C in rat brain.

Intermittent chaos, self-organization, and learning from synchronous synaptic activity in model neuron networks.

Wall-thickness and midwall-radius variations in ventricular mechanics.

Estimating the superiority of a drug to a placebo when all and only those patients at risk are treated with the drug.

Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex.

A second exopolysaccharide of Rhizobium meliloti strain SU47 that can function in root nodule invasion.

Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase.

Multigene families for anthracycline antibiotic production in Streptomyces peucetius.

Harmonic vibrations and thermodynamic stability of a DNA oligomer in monovalent salt solution.

Hydration forces between parallel DNA double helices: computer simulations.

Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation.

Evolution of mouse chromosome 17 and the origin of inversions associated with t haplotypes.

Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis.

Human immunodeficiency virus type 1 in spinal cords of acquired immunodeficiency syndrome patients with myelopathy: expression and replication in macrophages.

Direct and sex-specific stimulation by sex steroids of creatine kinase activity and DNA synthesis in rat bone.

Saposin A: second cerebrosidase activator protein.

Gestational changes in calbindin-D9k in rat uterus, yolk sac, and placenta: implications for maternal-fetal calcium transport and uterine muscle function.

Repair of N-methylpurines in specific DNA sequences in Chinese hamster ovary cells: absence of strand specificity in the dihydrofolate reductase gene.

Year: 1989 Volume: 86 Issue: 8

Year: 1989 Volume: 86 Issue: 7

Year: 1989 Volume: 86 Issue: 6

Year: 1989 Volume: 86 Issue: 5

Year: 1989 Volume: 86 Issue: 4

Year: 1989 Volume: 86 Issue: 3

Year: 1989 Volume: 86 Issue: 2

Year: 1989 Volume: 86 Issue: 1

Specific photoaffinity labeling of two plasma membrane polypeptides with an azido auxin.

Phytochrome induces changes in the immunodetectable level of a wall peroxidase that precede growth changes in maize seedlings.

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Bucana, C. Fidler, I. J. Schroit, A. J. Connor, J.
Description	Author Affiliation: Connor J ( Department of Cell Biology, University of Texas M. D. Anderson Cancer Center, Houston 77030.);
Abstract	Phosphatidylserine (PS) is asymmetrically distributed in mammalian cell membranes, being preferentially localized in the inner leaflet. Some studies have suggested that a disturbance in the normal asymmetric distribution of PS--e.g., PS exposure in the outer leaflet of the cell membrane, which can occur upon platelet activation as well as in certain pathologic red cells--serves as a potent procoagulant surface and as a signal for triggering their recognition by macrophages. These studies suggest that the regulation of PS distribution in cell membranes may be critical in controlling coagulation and in determining the survival of pathologic cells in the circulation. In this paper we describe a sensitive technique, based on PS-dependent prothrombinase complex activity, for assessing the amount of PS on the external leaflet of intact viable cells. Our results indicate that tumorigenic, undifferentiated murine erythroleukemic cells express 7- to 8-fold more PS in their outer leaflet than do their differentiated, nontumorigenic counterparts. Increased expression of PS in the tumorigenic cells directly correlated with their ability to be recognized and bound by macrophages.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	9
Volume Number	86
Language	English
Publisher	National Academy of Sciences
Publisher Date	1989-06-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	4-Chloro-7-nitrobenzofurazan Analogs & Derivatives Cell Membrane Metabolism Phosphatidylserines Thromboplastin Animals Cell Differentiation Erythrocytes Friend Murine Leukemia Virus Kinetics Leukemia, Erythroblastic, Acute Liposomes Macrophages Membrane Lipids Mice Thrombin Tumor Cells, Cultured Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in