NDLI: 5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system.

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5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system.

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5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Jessell, T. M. Molineaux, S. M. Julius, D. Axel, R.
Description	Author Affiliation: Molineaux SM ( Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, New York, NY 10032.);
Abstract	Neurons in rat central nervous system (CNS) that express 5-HT1c receptor mRNA have been localized by in situ hybridization histochemistry. The 5-HT1c receptor is expressed in a wide variety of cortical and subcortical neurons including hippocampal pyramidal neurons, neurons within most of the central monoaminergic cell groups, neurons in thalamic sensory relay nuclei, and neurons involved in the central processing and regulation of nociceptive transmission. Therefore, the 5-HT1c receptor is a prominent but poorly characterized central subclass of serotonin (5-HT) receptor. The distribution of the 5-HT1c receptor within the CNS is considerably more widespread than that of the structurally and functionally related 5-HT2 receptor.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	17
Volume Number	86
Language	English
Publisher	National Academy of Sciences
Publisher Date	1989-10-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Brain Metabolism RNA, Messenger Genetics Receptors, Serotonin Spinal Cord Animals Nucleic Acid Hybridization Organ Specificity RNA Probes Biosynthesis Research Support, Non-U.S. Gov't Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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