NDLI: Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1991 Volume: 88 Issue: 24

Year: 1991 Volume: 88 Issue: 23

Year: 1991 Volume: 88 Issue: 22

Year: 1991 Volume: 88 Issue: 21

Year: 1991 Volume: 88 Issue: 20

Year: 1991 Volume: 88 Issue: 19

Year: 1991 Volume: 88 Issue: 18

Year: 1991 Volume: 88 Issue: 17

Year: 1991 Volume: 88 Issue: 16

Year: 1991 Volume: 88 Issue: 15

Year: 1991 Volume: 88 Issue: 14

Year: 1991 Volume: 88 Issue: 13

Year: 1991 Volume: 88 Issue: 12

Year: 1991 Volume: 88 Issue: 11

Year: 1991 Volume: 88 Issue: 10

Year: 1991 Volume: 88 Issue: 9

Year: 1991 Volume: 88 Issue: 8

Year: 1991 Volume: 88 Issue: 7

Year: 1991 Volume: 88 Issue: 6

Year: 1991 Volume: 88 Issue: 5

Gene silencing in a polyploid homosporous fern: paleopolyploidy revisited.

Engineering the chloroplast genome: techniques and capabilities for chloroplast transformation in Chlamydomonas reinhardtii.

Transformation of a partial nopaline synthase gene into tobacco suppresses the expression of a resident wild-type gene.

Chloroplast DNA evidence for a North American origin of the Hawaiian silversword alliance (Asteraceae).

Evolution of diabroticite rootworm beetle (Chrysomelidae) receptors for Cucurbita blossom volatiles.

Nest-mate recognition based on heritable odors in the termite Microcerotermes arboreus.

Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumors.

Characteristics of erythroleukemia cells selected for vincristine resistance that have accelerated inducer-mediated differentiation.

Protein phosphatase inhibitor okadaic acid enhances transmitter release at neuromuscular junctions.

Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor.

Antennapedia homeobox peptide regulates neural morphogenesis.

Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding gene.

High-level synthesis of a heterologous milk protein in the mammary glands of transgenic swine.

Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end.

Heritable retroviral transgenes are highly expressed in chickens.

Endonucleolytic degradation of puf mRNA in Rhodobacter capsulatus is influenced by oxygen.

Pertussis toxin-sensitive G proteins are transported toward synaptic terminals by fast axonal transport.

Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells.

Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart.

Expressional potency of mRNAs encoding receptors and voltage-activated channels in the postmortem rat brain.

Transcriptional repression of the mouse insulin-responsive glucose transporter (GLUT4) gene by cAMP.

Construction of a uniform-abundance (normalized) cDNA library.

FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae.

Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression.

Macrophage heterogeneity occurs through a developmental mechanism.

D1 and D2 dopamine receptor mRNA in rat brain.

Mutational analysis of yeast vacuolar H(+)-ATPase.

A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia.

Characterization of a tachykinin peptide NK2 receptor transfected into murine fibroblast B82 cells.

Promoter region of the human platelet-derived growth factor A-chain gene.

Growth hormone inhibits activation of phosphatidylinositol phospholipase C in adipose plasma membranes: evidence for a growth hormone-induced change in G protein function.

Effects of site-directed mutagenesis at residues cysteine-31 and cysteine-184 on lecithin-cholesterol acyltransferase activity.

Lambda YES: a multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and Escherichia coli mutations.

Interaction of the v-rel protein with an NF-kappa B DNA binding site.

Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene.

Transfection of C6 glioma cells with connexin 43 cDNA: analysis of expression, intercellular coupling, and cell proliferation.

Modulation of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/quisqualate receptors by phospholipase A2: a necessary step in long-term potentiation?

Drosophila stimulatory G protein alpha subunit activates mammalian adenylyl cyclase but interacts poorly with mammalian receptors: implications for receptor-G protein interaction.

Skin toxicity determined in vitro by three-dimensional, native-state histoculture.

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.

Human microvascular endothelial cells express receptors for platelet-derived growth factor.

Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex.

Concerted evolution of duplicated protein-coding genes in Drosophila.

Purification of the regulatory protein AlgR1 and its binding in the far upstream region of the algD promoter in Pseudomonas aeruginosa.

Expression of the amyloid precursor protein gene in mouse oocytes and embryos.

Host-plant specialization in the Drosophila melanogaster species complex: a physiological, behavioral, and genetical analysis.

Mutasynthesis of siderophore analogues by Pseudomonas aeruginosa.

Eliminated chromatin of Ascaris contains a gene that encodes a putative ribosomal protein.

Branching pattern in the evolutionary tree for human mitochondrial DNA.

Monomeric IgG2a promotes maturation of bone-marrow macrophages and expression of the mannose receptor.

Dissociation of object and spatial visual processing pathways in human extrastriate cortex.

Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice.

Role of integration host factor in the regulation of the glnHp2 promoter of Escherichia coli.

Complementation of a yeast cell cycle mutant by an alfalfa cDNA encoding a protein kinase homologous to p34cdc2.

ToxR regulates the production of lipoproteins and the expression of serum resistance in Vibrio cholerae.

Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol.

Phosphorylation of the DNA-binding domain of nonhistone high-mobility group I protein by cdc2 kinase: reduction of binding affinity.

Isolation and characterization of yeast artificial chromosome clones linking the HLA-B and HLA-C loci.

Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteins.

Energetics of repacking a protein interior.

Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process.

Expression of v-src in a murine T-cell hybridoma results in constitutive T-cell receptor phosphorylation and interleukin 2 production.

A serum heterodimer from hagfish (Eptatretus stoutii) exhibits structural similarity and partial sequence identity with immunoglobulin.

Structural diversity in the Plasmodium falciparum merozoite surface antigen 2.

Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine.

Nerve growth factor corrects developmental impairments of basal forebrain cholinergic neurons in the trisomy 16 mouse.

Tunicamycin increases desensitization of acetylcholine receptors in cultured mouse muscle cells.

The speed of attentional shifts in the visual field.

An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.

Comparison of cloned genes provides evidence for intergenomic exchange of DNA in the evolution of a tobacco glucan endo-1,3-beta-glucosidase gene family.

Stage transitions in B-lymphocyte differentiation correlate with limited variations in nuclear proteins.

Chromosome microdissection and cloning in human genome and genetic disease analysis.

Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica.

Expressions of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes are stimulated by recombinant platelet-derived growth factor isomers.

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence.

Glutathione deficiency leads to mitochondrial damage in brain.

Signals for retention of transmembrane proteins in the endoplasmic reticulum studied with CD4 truncation mutants.

Canonical ordered cosmid library of the symbiotic plasmid of Rhizobium species NGR234.

Angiotensin II induces secretion of plasminogen activator inhibitor 1 and a tissue metalloprotease inhibitor-related protein from rat brain astrocytes.

Long-chain (sphingoid) bases inhibit multistage carcinogenesis in mouse C3H/10T1/2 cells treated with radiation and phorbol 12-myristate 13-acetate.

A cDNA encoding a human CCAAT-binding protein cloned by functional complementation in yeast.

The pharmacophore of debromoaplysiatoxin responsible for protein kinase C activation.

Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.

Glycosylation site-binding protein is not required for N-linked glycoprotein synthesis.

Direct evidence that ganglioside is an integral component of the thyrotropin receptor.

T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck.

Rabies virus nucleoprotein expressed in and purified from insect cells is efficacious as a vaccine.

Molecular characterization of a major nephritogenic domain in the autoantigen of anti-tubular basement membrane disease.

Differentiation of HL-60 leukemia by type I regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase.

Protein kinase C inhibitors prevent induction and continued expression of cell memory in Hermissenda type B photoreceptors.

Dipoles localized at helix termini of proteins stabilize charges.

Site and strand specificity of UVB mutagenesis in the SUP4-0 gene of yeast.

Year: 1991 Volume: 88 Issue: 4

Year: 1991 Volume: 88 Issue: 3

Year: 1991 Volume: 88 Issue: 2

Year: 1991 Volume: 88 Issue: 1

Two-dimensional life?

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Price, E. R. Baker, C. H. Mckeon, F. D. Walsh, C. T. Zydowsky, L. D. Jin, M. J.
Description	Author Affiliation: Price ER ( Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.);
Abstract	We report the cloning and characterization of a cDNA encoding a second human cyclosporin A-binding protein (hCyPB). Homology analyses reveal that hCyPB is a member of the cyclophilin B (CyPB) family, which includes yeast CyPB, Drosophila nina A, and rat cyclophilin-like protein. This family is distinguished from the cyclophilin A (CyPA) family by the presence of endoplasmic reticulum (ER)-directed signal sequences. hCyPB has a hydrophobic leader sequence not found in hCyPA, and its first 25 amino acids are removed upon expression in Escherichia coli. Moreover, we show that hCyPB is a peptidyl-prolyl cis-trans isomerase which can be inhibited by cyclosporin A. These observations suggest that other members of the CyPB family will have similar enzymatic properties. Sequence comparisons of the CyPB proteins show a central, 165-amino acid peptidyl-prolyl isomerase and cyclosporin A-binding domain, flanked by variable N-terminal and C-terminal domains. These two variable regions may impart compartmental specificity and regulation to this family of cyclophilin proteins containing the conserved core domain. Northern blot analyses show that hCyPB mRNA is expressed in the Jurkat T-cell line, consistent with its possible target role in cyclosporin A-mediated immunosuppression.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	5
Volume Number	88
Language	English
Publisher	National Academy of Sciences
Publisher Date	1991-04-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Amino Acid Isomerases Genetics Carrier Proteins Multigene Family Protein Sorting Signals Metabolism Amino Acid Sequence Cell Line Cloning, Molecular Endothelium, Vascular Enzymology Escherichia Coli Gene Library Kinetics Molecular Sequence Data Oligonucleotide Probes Peptidylprolyl Isomerase Polymerase Chain Reaction Sequence Homology, Nucleic Acid Comparative Study Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in