NDLI: Chronic cardiac rejection: identification of five upregulated genes in transplanted hearts by differential mRNA display.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1994 Volume: 91 Issue: 26

Year: 1994 Volume: 91 Issue: 26 Suppl

Year: 1994 Volume: 91 Issue: 25

Year: 1994 Volume: 91 Issue: 24

Year: 1994 Volume: 91 Issue: 23

Year: 1994 Volume: 91 Issue: 22

Year: 1994 Volume: 91 Issue: 21

Year: 1994 Volume: 91 Issue: 20

Year: 1994 Volume: 91 Issue: 19

Year: 1994 Volume: 91 Issue: 18

Year: 1994 Volume: 91 Issue: 17

Year: 1994 Volume: 91 Issue: 16

Year: 1994 Volume: 91 Issue: 15

Year: 1994 Volume: 91 Issue: 14

Trapped electron cloud bolometer relying on frequency shift.

Casimir light: field pressure.

Expression of an auxin- and cytokinin-regulated gene in cambial region in Zinnia.

Disruption of hydrogen bonding between plant cell wall polymers by proteins that induce wall extension.

Timing of fungal invasion using host's ripening hormone as a signal.

The aquaporin family of molecular water channels.

Cyclic nucleotide- and inositol phosphate-gated ion channels in lobster olfactory receptor neurons.

Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells.

Three distinct human thymopoietins are derived from alternatively spliced mRNAs.

Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution.

Nitric oxide mediates sexual behavior in female rats.

Axonal transport of herpes simplex virions to epidermal cells: evidence for a specialized mode of virus transport and assembly.

Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants.

Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA.

Two-photon scanning photochemical microscopy: mapping ligand-gated ion channel distributions.

On producing more complexity than entropy in replication.

The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor.

Drosophila telomere transposon HeT-A produces a transcript with tightly bound protein.

Alternative splicing generates secretory isoforms of human CD1.

Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains.

Paradoxical fate and biological action of peroxynitrite on human platelets.

The Fanconi anemia polypeptide FACC is localized to the cytoplasm.

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

Structure and polymorphism of the mouse prion protein gene.

Inference of human evolution through cladistic analysis of nuclear DNA restriction polymorphisms.

An array of early differentiating cones precedes the emergence of the photoreceptor mosaic in the fetal monkey retina.

Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity.

Identification of residues in the Mu transposase essential for catalysis.

The conundrum of nonclassical major histocompatibility complex genes.

Emerging complexity of odor transduction.

A second lineage of mammalian major histocompatibility complex class I genes.

Regulation of phospholipase A2 in human leukemia cell lines: its implication for intracellular signaling.

Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A.

Infection and immunoregulation of T lymphocytes by parainfluenza virus type 3.

Partial rescue of a lethal phenotype of fragile bones in transgenic mice with a chimeric antisense gene directed against a mutated collagen gene.

LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit.

A membrane-delimited pathway of G-protein regulation of the guard-cell inward K+ channel.

Change in male secondary sexual characters in artificial interspecific hybrid populations.

Mutator phenotypes in human colorectal carcinoma cell lines.

Functional redundancy: the respective roles of the two sloppy paired genes in Drosophila segmentation.

Central effects of baroreceptor activation in humans: attenuation of skeletal reflexes and pain perception.

High-affinity alpha-thrombin binding to platelet glycoprotein Ib alpha: identification of two binding domains.

Different event-related patterns of gamma-band power in brain waves of fast- and slow-reacting subjects.

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.

Domain structure of a mammalian myosin I beta.

A DNA-binding activity, TRAC, specific for the TRA element of the transferrin receptor gene copurifies with the Ku autoantigen.

DNA-binding and trans-activation properties of Drosophila E2F and DP proteins.

Nonneutral evolution at the mitochondrial NADH dehydrogenase subunit 3 gene in mice.

Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis.

Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes.

Fatty acid synthesis: a potential selective target for antineoplastic therapy.

Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells.

Sak, a murine protein-serine/threonine kinase that is related to the Drosophila polo kinase and involved in cell proliferation.

The plasma flux and oxidation rate of ornithine adaptively decline with restricted arginine intake.

Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells.

Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114.

Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.

A requirement of hydrophobic and basic amino acid residues for substrate recognition by Ca2+/calmodulin-dependent protein kinase Ia.

Host cell responses to Listeria monocytogenes infection include differential transcription of host stress genes involved in signal transduction.

The POU domain protein Tst-1 and papovaviral large tumor antigen function synergistically to stimulate glia-specific gene expression of JC virus.

Multiple pathways of copy control of gamma replicon of R6K: mechanisms both dependent on and independent of cooperativity of interaction of tau protein with DNA affect the copy number.

Expression of a glycosylphosphatidylinositol-anchored Trypanosoma brucei transferrin-binding protein complex in insect cells.

The biological clock that measures the mitotic life-span of mouse embryo fibroblasts continues to function in the presence of simian virus 40 large tumor antigen.

Switch in gap junction protein expression is associated with selective changes in junctional permeability during keratinocyte differentiation.

Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.

Chronic cardiac rejection: identification of five upregulated genes in transplanted hearts by differential mRNA display.

Genetic variants of human serum albumin in Italy: point mutants and a carboxyl-terminal variant.

A role for a eukaryotic GrpE-related protein, Mge1p, in protein translocation.

Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.

Rapid morphological radiation and convergence among races of the butterfly Heliconius erato inferred from patterns of mitochondrial DNA evolution.

Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development.

Structural organization of the Helicoverpa zea gene encoding the precursor protein for pheromone biosynthesis-activating neuropeptide and other neuropeptides.

Loss of a histidine residue at the active site of S-locus ribonuclease is associated with self-compatibility in Lycopersicon peruvianum.

Altered natural killer cell repertoire in Tap-1 mutant mice.

Positive selection of self- and alloreactive CD8+ T cells in Tap-1 mutant mice.

Creation and phenotypic analysis of alpha-lactalbumin-deficient mice.

Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. (Journal: Proceedings of the National Academy of Sciences of the United States of America Volume: 91 Issue: 14)

Phospholipase C-gamma 1 can induce DNA synthesis by a mechanism independent of its lipase activity.

Reversal of cell determination in yeast meiosis: postcommitment arrest allows return to mitotic growth.

Characterization of mutations induced by ethylnitrosourea in seminiferous tubule germ cells of transgenic B6C3F1 mice.

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes.

Peptide segment ligation strategy without use of protecting groups.

Structure, function, and evolution of mouse TL genes, nonclassical class I genes of the major histocompatibility complex.

The Fenton oxidation mechanism: reactivities of biologically relevant substrates with two oxidizing intermediates differ from those predicted for the hydroxyl radical.

A yeast system for expression of human cystathionine beta-synthase: structural and functional conservation of the human and yeast genes.

Experimental control of neoplastic progression in cell populations: Foulds' rules revisited.

Active site of the mRNA-capping enzyme guanylyltransferase from Saccharomyces cerevisiae: similarity to the nucleotidyl attachment motif of DNA and RNA ligases.

Drosophila mode of metamerization in the embryogenesis of the lepidopteran insect Manduca sexta.

A fluorescence-based assay for monitoring helicase activity.

Differential regulation of an auxin-producing nitrilase gene family in Arabidopsis thaliana.

High-level expression and deletion mutagenesis of human tryptophan hydroxylase.

Bloom syndrome: an analysis of consanguineous families assigns the locus mutated to chromosome band 15q26.1.

Induction of differentiation in HL60 cells by the reduction of extrachromosomally amplified c-myc.

Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.

Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes.

T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus.

Year: 1994 Volume: 91 Issue: 13

Year: 1994 Volume: 91 Issue: 12

Year: 1994 Volume: 91 Issue: 11

Year: 1994 Volume: 91 Issue: 10

Year: 1994 Volume: 91 Issue: 9

Year: 1994 Volume: 91 Issue: 8

Year: 1994 Volume: 91 Issue: 7

Year: 1994 Volume: 91 Issue: 6

Year: 1994 Volume: 91 Issue: 5

Year: 1994 Volume: 91 Issue: 4

Year: 1994 Volume: 91 Issue: 3

Year: 1994 Volume: 91 Issue: 2

Year: 1994 Volume: 91 Issue: 1

Impact melting of frozen oceans on the early Earth: Implications for the origin of life

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Chronic cardiac rejection: identification of five upregulated genes in transplanted hearts by differential mRNA display.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wyner, L. R. Karnovsky, M. J. Liang, P. Utans, U. Russell, M. E.
Description	Author Affiliation: Utans U ( Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, MA 02115.);
Abstract	Transplant arteriosclerosis, the major manifestation of chronic rejection, develops after allogeneic (Lewis to F344) but not syngeneic (Lewis to Lewis) rat cardiac transplantation. To identify transcriptionally regulated mediators associated with chronic cardiac rejection, we adapted the differential mRNA display technique for in vivo transplant specimens. Gene transcript patterns in four allogeneic hearts showing early signs of chronic rejection were compared with those in two syngeneic hearts exposed to the same surgical procedure but histologically normal. Twelve differentially expressed cDNA bands were identified. We improved the probability of isolating one or more allograft-specific cDNAs from a single display band by first using recovered and reamplified PCR products as probes in RNA blot analysis. cDNA fragments cloned from individual bands were then used in a second RNA blot analysis, which allowed for the correlation of specific mRNA transcripts with cDNA clones. Five cDNA clones produced time-dependent, allograft-specific hybridization. Sequence analysis demonstrated that two of these cDNAs corresponded to unknown genes, whereas the other three represented known genes not previously associated with chronic rejection. The latter group included the macrophage lectin specific for galactose/N-acetylgalactosamine (a cell-surface receptor), the nuclear P1 gene (a homologue of a yeast replication protein), and a ubiquitin-like gene. Our application of the differential display technique allowed the direct identification of potential mediators under in vivo conditions that preserve the environment of the disease process--including infiltrating cell populations critical to the inflammatory response.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	14
Volume Number	91
Language	English
Publisher	National Academy of Sciences
Publisher Date	1994-08-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Gene Expression Regulation Graft Rejection Genetics Heart Transplantation Physiology Myocardium Metabolism RNA, Messenger Biosynthesis Animals Cloning, Molecular DNA Primers DNA, Complementary Immunology Inflammation Lectins Molecular Sequence Data Nuclear Proteins Polymerase Chain Reaction Rats, Inbred F344 Rats, Inbred Lew Sequence Homology, Nucleic Acid Transcription, Genetic Transplantation, Heterotopic Transplantation, Homologous Transplantation, Isogeneic Ubiquitins Comparative Study Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in