NDLI: Opportunities await.

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Introduction to 'From the Academy'.

Opportunities await.

Colleges of agriculture at the land grant universities: public service and public policy. An excerpt from the Executive Summary of the National Research Council Report.

The U.S. National Academy of Sciences--in service to science and society.

Workshop on schizophrenia.

Expression pattern of HIV-1 coreceptors on T cells: implications for viral transmission and lymphocyte homing.

Choosing the right sugar: how polymerases select a nucleotide substrate.

Rapid, sensitive structure analysis of oligosaccharides.

Ensemble quantum computing by NMR spectroscopy.

One gene in diamondback moth confers resistance to four Bacillus thuringiensis toxins.

Persistence in muscle of an adenoviral vector that lacks all viral genes.

Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo.

A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor alpha chain.

'Peptabody': a new type of high avidity binding protein.

Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)

Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters.

Development of 'substrate-trapping' mutants to identify physiological substrates of protein tyrosine phosphatases.

Conformation-dependent phosphorylation of p53.

Chirality of DNA trefoils: implications in intramolecular synapsis of distant DNA segments.

Detection of changes in pairwise interactions during allosteric transitions: coupling between local and global conformational changes in GroEL.

A Xenopus oocyte β subunit: Evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit

The two alpha subunits of Escherichia coli RNA polymerase are asymmetrically arranged and contact different halves of the DNA upstream element.

Structure and function in rhodopsin: peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase.

Galactose-dependent reversible interaction of Gal3p with Gal80p in the induction pathway of Gal4p-activated genes of Saccharomyces cerevisiae.

$Gα_{o}$ is necessary for muscarinic regulation of $Ca^{2+}$ channels in mouse heart

Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1.

A heparin-binding synthetic peptide of heparin/heparan sulfate-interacting protein modulates blood coagulation activities.

Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor.

Benzo[a]pyrene diol epoxide-DNA cis adduct formation through a trans chlorohydrin intermediate.

Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3' end of the RNA intact and extruded.

Site-specific mutagenesis reveals differences in the structural bases for tight binding of RNase inhibitor to angiogenin and RNase A.

Electron diffraction studies of light-induced conformational changes in the Leu-93 --> Ala bacteriorhodopsin mutant.

Cooperative effects of photodynamic treatment of cells in microcolonies.

Submillisecond protein folding kinetics studied by ultrarapid mixing.

Direct in vivo measurement of targeted binding in a human tumor xenograft.

Direct phase determination in protein electron crystallography: the pseudo-atom approximation.

Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation.

$Na^{+}$ pump low and high ouabain affinity α subunit isoforms are differently distributed in cells

Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation.

DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer.

Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.

Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion.

GTP-bound forms of rab6 induce the redistribution of Golgi proteins into the endoplasmic reticulum.

Apical sorting of hepatitis B surface antigen (HBsAg) is independent of N-glycosylation and glycosylphosphatidylinositol-anchored protein segregation.

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage.

Multiple promoter elements differentially regulate the expression of the mouse tenascin gene.

Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development.

Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population.

A single and early migration for the peopling of the Americas supported by mitochondrial DNA sequence data.

Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons.

Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation.

Incomplete endoplasmic reticulum (ER) retention in immature thymocytes as revealed by surface expression of 'ER-resident' molecular chaperones.

Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection.

Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome.

The antigen-binding domain of a human IgG-anti-F(ab')2 autoantibody.

Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization.

A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening.

syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction.

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes.

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis.

Targeting RNA decay with 2',5' oligoadenylate-antisense in respiratory syncytial virus-infected cells.

Antigen presentation in retroviral vector-mediated gene transfer in vivo.

Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter.

Peptide inhibition of glomerular deposition of an anti-DNA antibody.

Transfection and overexpression of the calcium binding protein calbindin-D28k results in a stimulatory effect on insulin synthesis in a rat beta cell line (RIN 1046-38).

Glutathione deficiency is associated with impaired survival in HIV disease.

A genetic analysis of integrin function: Glanzmann thrombasthenia in vitro.

sigma54, a vital protein for Myxococcus xanthus.

Instrumental conditioning of fast (20- to 50-Hz) oscillations in corticothalamic networks.

Differential pre- and postsynaptic modulation of chemical transmission in the squid giant synapse by tyrosine phosphorylation.

Identification of components of a phosphoinositide signaling pathway in retinal rod outer segments.

Changes in multiple brain regions underlie species differences in a complex, congenital behavior.

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage.

D-aspartate localizations imply neuronal and neuroendocrine roles.

Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine.

Blockage of 5HT2C serotonin receptors by fluoxetine (Prozac).

Blockage of muscle and neuronal nicotinic acetylcholine receptors by fluoxetine (Prozac).

Pore size of the malaria parasite's nutrient channel.

Cloning of cDNA and estrogen-induced hepatic gene expression for choriogenin H, a precursor protein of the fish egg envelope (chorion).

Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses.

Working underground: Respiratory adaptations in the blind mole rat

Somatotropic actions of the homologous growth hormone and prolactins in the euryhaline teleost, the tilapia, Oreochromis mossambicus.

A mutation in the putative RNA polymerase gene inhibits nonhomologous, but not homologous, genetic recombination in an RNA virus.

Rapid, transient, and highly localized induction of plastidial omega-3 fatty acid desaturase mRNA at fungal infection sites in Petroselinum crispum.

The MUR1 gene of Arabidopsis thaliana encodes an isoform of GDP-D-mannose-4,6-dehydratase, catalyzing the first step in the de novo synthesis of GDP-L-fucose.

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