NDLI: Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2002 Volume: 99 Issue: 26

Year: 2002 Volume: 99 Issue: 25

Year: 2002 Volume: 99 Issue: 24

Year: 2002 Volume: 99 Issue: 23

Year: 2002 Volume: 99 Issue: 22

Year: 2002 Volume: 99 Issue: 21

Year: 2002 Volume: 99 Issue: 20

Year: 2002 Volume: 99 Issue: 19

The mechanism of type IA topoisomerases.

Optimizing grain yields reduces $CH_{4}$ emissions from rice paddy fields

The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG.

Cytochrome c folding pathway: kinetic native-state hydrogen exchange.

Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility.

Mechanism by which 2,2,2-trifluoroethanol/water mixtures stabilize secondary-structure formation in peptides: A molecular dynamics study

Cloning the vaccinia virus genome as a bacterial artificial chromosome in Escherichia coli and recovery of infectious virus in mammalian cells.

The antiangiogenic activity of cleaved high molecular weight kininogen is mediated through binding to endothelial cell tropomyosin.

Mutagenesis and repair by low doses of alpha radiation in mammalian cells.

Friction traced to the single atom.

Biosynthesis of terpenes: studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase.

Role of the C-terminal propeptide in the activity and maturation of gamma -interferon-inducible lysosomal thiol reductase (GILT).

Evidence for van der Waals adhesion in gecko setae.

Trojan particles: large porous carriers of nanoparticles for drug delivery.

Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae.

Rapid atmospheric $CO_{2}$ changes associated with the 8,200-years-B.P. cooling event

Serotonin mediates food-odor associative learning in the nematode Caenorhabditiselegans.

Somatic hypermutation of the AID transgene in B and non-B cells.

Heterozygous alpha 2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists.

Whole-genome comparative analysis of three phytopathogenic Xylella fastidiosa strains.

M-FISH analysis shows that complex chromosome aberrations induced by alpha -particle tracks are cumulative products of localized rearrangements.

Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice.

Genomic profiles of clinical and environmental isolates of Vibrio cholerae O1 in cholera-endemic areas of Bangladesh

Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

Cortical representation of first and second pain sensation in humans.

CFTR chloride channels are regulated by a SNAP-23/syntaxin 1A complex.

Revisiting the kinetics of nitric oxide (NO) binding to soluble guanylate cyclase: the simple NO-binding model is incorrect.

Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation.

Chronic treatment with nitric oxide-releasing aspirin reduces plasma low-density lipoprotein oxidation and oxidative stress, arterial oxidation-specific epitopes, and atherogenesis in hypercholesterolemic mice.

8-Oxoguanine rearranges the active site of human topoisomerase I.

Nitrogen monoxide-mediated control of ferritin synthesis: Implications for macrophage iron homeostasis

Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels

Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function.

A protease assay for two-photon crosscorrelation and FRET analysis based solely on fluorescent proteins.

MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer.

Dual localization of human DNA topoisomerase IIIalpha to mitochondria and nucleus.

Type III secretion systems and the evolution of mutualistic endosymbiosis.

Isolation of an Arabidopsis mutant lacking vitamin E and identification of a cyclase essential for all tocopherol biosynthesis.

Inhibition of amyloid-beta aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761.

Multiple thyroid hormone-induced muscle growth and death programs during metamorphosis in Xenopus laevis.

STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.

Electrical and chemical synapses among parvalbumin fast-spiking GABAergic interneurons in adult mouse neocortex.

Identifying novel transcripts and novel genes in the human genome by using novel SAGE tags.

The structural basis for the transition from Ras-GTP to Ras-GDP.

Protein assembly and heat stability in developing thylakoid membranes during greening.

Purification and electron microscopic visualization of functional human spliceosomes.

The binding protein of corticotropin-releasing factor: ligand-binding site and subunit structure.

The skeletal muscle $Ca^{2+}$ release channel has an oxidoreductase-like domain

Singularity in budding: a role for the evolutionarily conserved small GTPase Cdc42p.

Identification of a human telomerase reverse transcriptase peptide of low affinity for HLA A2.1 that induces cytotoxic T lymphocytes and mediates lysis of tumor cells.

Evolutionary analysis of Arabidopsis, cyanobacterial, and chloroplast genomes reveals plastid phylogeny and thousands of cyanobacterial genes in the nucleus.

A functional polymorphism in the promoter of the progesterone receptor gene associated with endometrial cancer risk.

RecX protein abrogates ATP hydrolysis and strand exchange promoted by RecA: insights into negative regulation of homologous recombination.

Crystal structure of calcineurin–cyclophilin–cyclosporin shows common but distinct recognition of immunophilin–drug complexes

Integrated classification of lung tumors and cell lines by expression profiling.

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo.

Engineering growing tissues.

Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.

Act locally and think globally: intracerebral testosterone implants induce seasonal-like growth of adult avian song control circuits.

A simple method for probing the mechanical unfolding pathway of proteins in detail.

Mouse transferrin receptor 1 is the cell entry receptor for mouse mammary tumor virus.

The two-component system BvrR/BvrS essential for Brucella abortus virulence regulates the expression of outer membrane proteins with counterparts in members of the Rhizobiaceae.

A global pH sensor: Agrobacterium sensor protein ChvG regulates acid-inducible genes on its two chromosomes and Ti plasmid.

Molecular cloning and functional expression of the first insect FMRFamide receptor.

A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity.

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade.

Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.

Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest.

Physical constraints and functional characteristics of transcription factor-DNA interaction.

Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19

Inhibition of hypochlorous acid-induced cellular toxicity by nitrite.

Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice.

Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.

A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19.

Convergent evolution sheds light on the anti-β-elimination mechanism common to family 1 and 10 polysaccharide lyases

A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes.

Experimental control of pancreatic development and maintenance.

Folate synthesis in plants: the first step of the pterin branch is mediated by a unique bimodular GTP cyclohydrolase I.

Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis.

Ubiquitination of inducible nitric oxide synthase is required for its degradation.

Directional selection is the primary cause of phenotypic diversification.

Crosslinking of membrane-embedded cysteines reveals contact points in the EmrE oligomer

$G_{βγ}-independent$ constitutive association of $G_{αs}$ with SHP-1 and angiotensin II receptor $AT_{2}$ is essential in $AT_{2}-mediated$ ITIM-independent activation of SHP-1

Application of charge density methods to a protein model compound: calculation of Coulombic intermolecular interaction energies from the experimental charge density.

The ribosome filter hypothesis.

Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis.

Type IA DNA topoisomerases: strictly one step at a time.

Photosynthate allocations in rice plants: food production or atmospheric methane?

The genomics of symbiosis: hosts keep the baby and the bath water.

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice.

Year: 2002 Volume: 99 Issue: 18

Year: 2002 Volume: 99 Issue: 17

Year: 2002 Volume: 99 Issue: 16

Year: 2002 Volume: 99 Issue: 15

Year: 2002 Volume: 99 Issue: 14

Year: 2002 Volume: 99 Issue: 13

Year: 2002 Volume: 99 Issue: 12

Year: 2002 Volume: 99 Issue: 11

Year: 2002 Volume: 99 Issue: 10

Year: 2002 Volume: 99 Issue: 9

Year: 2002 Volume: 99 Issue: 8

Year: 2002 Volume: 99 Issue: 7

Year: 2002 Volume: 99 Issue: 6

Year: 2002 Volume: 99 Issue: 5

Year: 2002 Volume: 99 Issue: 4

Year: 2002 Volume: 99 Issue: Suppl 4

Year: 2002 Volume: 99 Issue: 3

Year: 2002 Volume: 99 Issue: Suppl 3

Year: 2002 Volume: 99 Issue: 2

Year: 2002 Volume: 99 Issue: Suppl 2

Year: 2002 Volume: 99 Issue: 1

Year: 2002 Volume: 99 Issue: Suppl 1

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Goritchenko, Luda Greengard, Paul Irwin, Nina Chao, Steven Horiuchi, Atsuko Nairn, Angus C. Benowitz, Larry I.
Description	Author Affiliation: Irwin N ( Department of Neurosurgery, Children's Hospital, Boston, MA 02115, USA.);
Abstract	The membrane phosphoprotein GAP-43 is involved in axon growth and synaptic plasticity. In PC12 pheochromocytoma cells, induction of a neuronal phenotype by nerve growth factor (NGF) is accompanied by a marked increase in GAP-43 levels. NGF regulates GAP-43 expression by altering the half-life of its mRNA. We report here that the phosphoprotein ARPP-19 mediates this regulation. In an NGF-dependent manner, ARPP-19 bound to a region in the 3' end of GAP-43 mRNA previously found to be important for regulating the half-life of the mRNA. Overexpression of wild-type ARPP-19 in PC12 cells increased the NGF-dependent expression of a reporter construct linked to the critical 3' region of GAP-43 mRNA. Mutation of serine 104, the site of phosphorylation by protein kinase A in ARPP-19, to either alanine or aspartate abolished this regulation in PC12 cells. These findings demonstrate that ARPP-19 is an important link between NGF signaling and post-transcriptional control of neuronal gene expression.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	19
Volume Number	99
Language	English
Publisher	National Academy of Sciences
Publisher Date	2002-09-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	GAP-43 Protein Genetics Nerve Growth Factor Pharmacology Phosphoproteins Metabolism RNA, Messenger Animals Binding Sites Gene Expression Regulation Molecular Sequence Data Mutagenesis, Site-Directed PC12 Cells Chemistry Protein Processing, Post-Translational RNA Stability Drug Effects Sequence Homology, Nucleic Acid Serine Signal Transduction Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in