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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Uerpmann, Margarethe Abdussamad, Abdussamad M. Salim, Bashir Burger, Pamela A. Pitt, Daniel Dessie, Tadelle Mohandesan, Elmira Raziq, Abdul Orozco-terwengel, Pablo Uerpmann, Hans-peter Peters, Joris De Cupere, Bea Banabazi, Mohammad H. Almathen, Faisal Hofreiter, Michael Al-eknah, Marzook Charruau, Pauline Hanotte, Olivier Faye, Bernard Magee, Peter Walzer, Chris Alnaqeeb, Majed A. Mwacharo, Joram M. Abdelhadi, Omer M. |
| Description | Author Affiliation: Almathen F ( Department of Veterinary Public Health and Animal Husbandry, College of Veterinary Medicine and Animal Resources, King Faisal University, 400 Al-Hasa, Saudi Arabia); Charruau P ( Research Institute of Wildlife Ecology, Vetmeduni Vienna, 1160 Vienna, Austria); Mohandesan E ( Research Institute of Wildlife Ecology, Vetmeduni Vienna, 1160 Vienna, Austria); Mwacharo JM ( Genetics, Ecology and Evolution, School of Life Sciences, University of Nottingham, NG7 2RD Nottingham, United Kingdom); Orozco-terWengel P ( School of Biosciences, Cardiff University, Cardiff CF10 3AX, Wales, United Kingdom); Pitt D ( School of Biosciences, Cardiff University, Cardiff CF10 3AX, Wales, United Kingdom); Abdussamad AM ( Department of Animal Science, Faculty of Agriculture, Bayero University, PMB 3011, Kano State, Nigeria); Uerpmann M ( Institut für Naturwissenschaftliche Archäologie, Abteilung Archäozoologie, Universität Tübingen, 7207 Tuebingen, Germany); Uerpmann HP ( Institut für Naturwissenschaftliche Archäologie, Abteilung Archäozoologie, Universität Tübingen, 7207 Tuebingen, Germany); De Cupere B ( Department of Paleontology, Royal Belgian Institute of Natural Sciences, 1000 Brussels, Belgium); Magee P ( Department of Classical and Near Eastern Archaeology, Bryn Mawr College, Bryn Mawr, PA 19010); Alnaqeeb MA ( Department of Biological Sciences, Faculty of Science, Kuwait University, Safat 13060, Kuwait); Salim B ( Department of Parasitology, Faculty of Veterinary Medicine, University of Khartoum, Khartoum-North 13314, Sudan); Raziq A ( Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences, Uthal 90150, Pakistan); Dessie T ( Animal Biosciences, International Livestock Research Institute, Addis Ababa 1000, Ethiopia); Abdelhadi OM ( Department of Animal Production, Faculty of Natural Resources and Environmental Studies, University of Kordofan, Khartoum 11111, Sudan); Banabazi MH ( Department of Biotechnology, Animal Science Research Institute of Iran, 3146618361 Karaj, Iran); Al-Eknah M ( Department of Clinical Studies, College of Veterinary Medicine and Animal Resources, King Faisal University, 1757 Al-Hasa, Saudi Arabia); Walzer C ( Institute of Population Genetics, Vetmeduni Vienna, 1210 Vienna, Austria); Faye B ( Centre de Coopération Internationale en Recherche Agronomique pour le Développement-Environnements et Sociétés, UMR 112, Campus International de Baillarguet, TAC/112A, 34398 Montpellier, France); Hofreiter M ( Department of Mathematics and Natural Sciences, Evolutionary and Adaptive Genomics, Institute for Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany); Peters J ( Department of Veterinary Sciences, Institute of Palaeoanatomy, Domestication Research and the History of Veterinary Medicine, Ludwig-Maximilians-Universität München (LMU Munich), 80539 Munich, Germany); Hanotte O ( Genetics, Ecology and Evolution, School of Life Sciences, University of Nottingham, NG7 2RD Nottingham, United Kingdom); Burger PA ( Research Institute of Wildlife Ecology, Vetmeduni Vienna, 1160 Vienna, Austria); |
| Abstract | Dromedaries have been fundamental to the development of human societies in arid landscapes and for long-distance trade across hostile hot terrains for 3,000 y. Today they continue to be an important livestock resource in marginal agro-ecological zones. However, the history of dromedary domestication and the influence of ancient trading networks on their genetic structure have remained elusive. We combined ancient DNA sequences of wild and early-domesticated dromedary samples from arid regions with nuclear microsatellite and mitochondrial genotype information from 1,083 extant animals collected across the species' range. We observe little phylogeographic signal in the modern population, indicative of extensive gene flow and virtually affecting all regions except East Africa, where dromedary populations have remained relatively isolated. In agreement with archaeological findings, we identify wild dromedaries from the southeast Arabian Peninsula among the founders of the domestic dromedary gene pool. Approximate Bayesian computations further support the 'restocking from the wild' hypothesis, with an initial domestication followed by introgression from individuals from wild, now-extinct populations. Compared with other livestock, which show a long history of gene flow with their wild ancestors, we find a high initial diversity relative to the native distribution of the wild ancestor on the Arabian Peninsula and to the brief coexistence of early-domesticated and wild individuals. This study also demonstrates the potential to retrieve ancient DNA sequences from osseous remains excavated in hot and dry desert environments. |
| ISSN | 00278424 |
| e-ISSN | 10916490 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Issue Number | 24 |
| Volume Number | 113 |
| Language | English |
| Publisher | National Academy of Sciences |
| Publisher Date | 2016-06-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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