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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Wannamethee, S. G. Shaper, A. G. Walker, M. |
| Description | Author Affiliation: Shaper AG ( Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London.); |
| Abstract | OBJECTIVE: To determine the body mass index associated with the lowest morbidity and mortality. DESIGN: Prospective study of a male cohort. SETTING: One general practice in each of 24 British towns. SUBJECTS: 7735 men aged 40-59 years at screening. MAIN OUTCOME MEASURES: All cause death rate, heart attacks, and stroke (fatal and non-fatal) and development of diabetes, or any of these outcomes (combined end point) over an average follow up of 14.8 years. RESULTS: There were 1271 deaths from all causes, 974 heart attacks, 290 strokes, and 245 new cases of diabetes mellitus. All cause mortality was increased only in men with a body mass index (kg/m2) < 20 and in men with an index > or = 30. However, risk of cardiovascular death, heart attack, and diabetes increased progressively from an index of < 20 even after age, smoking, social class, alcohol consumption, and physical activity were adjusted for. For the combined end point the lowest risks were seen for an index of 20.0-23.9. In never smokers and former smokers, deaths from any cause rose progressively from an index of 20.0-21.9 and for the combined end point, from 20.0-23.9. Age adjusted levels of a wide range of cardiovascular risk factors rose or fell progressively from an index < 20. CONCLUSION: A healthy body mass index in these middle aged British men seems to be about 22. |
| ISSN | 09598138 |
| e-ISSN | 17561833 |
| Journal | BMJ (British Medical Journal) |
| Issue Number | 7090 |
| Volume Number | 314 |
| Language | English |
| Publisher | British Medical Journal Publishing Group |
| Publisher Date | 1997-06-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Body Weight Cerebrovascular Disorders Prevention & Control Coronary Disease Diabetes Mellitus Body Mass Index Cause Of Death Cohort Studies Follow-Up Studies Health Behavior Health Policy Health Promotion Life Style Prospective Studies Risk Factors Smoking Research Support, Non-U.S. Gov't Medicine |
| Content Type | Text |
| Resource Type | Article |
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