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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Bhattacharya, Siladitya Bhattacharya, Sohinee Smith, Norman C. Love, Eleanor R. |
| Spatial Coverage | Scotland |
| Description | Author Affiliation: Love ER ( University of Aberdeen, Aberdeen.); |
| Abstract | Objective To determine the optimum interpregnancy interval after miscarriage in a first recorded pregnancy. Design Population based retrospective cohort study. Setting Scottish hospitals between 1981 and 2000. Participants 30 937 women who had a miscarriage in their first recorded pregnancy and subsequently became pregnant. Main outcome measures The primary end point was miscarriage, live birth, termination, stillbirth, or ectopic pregnancy in the second pregnancy. Secondary outcomes were rates of caesarean section and preterm delivery, low birthweight infants, pre-eclampsia, placenta praevia, placental abruption, and induced labour in the second pregnancy. Results Compared with women with an interpregnancy interval of 6-12 months, those who conceived again within six months were less likely to have another miscarriage (adjusted odds ratio 0.66, 95% confidence interval 0.57 to 0.77), termination (0.43, 0.33 to 0.57), or ectopic pregnancy (0.48, 0.34 to 0.69). Women with an interpregnancy interval of more than 24 months were more likely to have an ectopic second pregnancy (1.97, 1.42 to 2.72) or termination (2.40, 1.91 to 3.01). Compared with women with an interpregnancy interval of 6-12 months, women who conceived again within six months and went on to have a live birth in the second pregnancy were less likely to have a caesarean section (0.90, 0.83 to 0.98), preterm delivery (0.89, 0.81 to 0.98), or infant of low birth weight (0.84, 0.71 to 0.89) but were more likely to have an induced labour (1.08, 1.02 to 1.23). Conclusions Women who conceive within six months of an initial miscarriage have the best reproductive outcomes and lowest complication rates in a subsequent pregnancy. |
| ISSN | 09598138 |
| e-ISSN | 17561833 |
| Journal | BMJ (British Medical Journal) |
| Volume Number | 341 |
| Language | English |
| Publisher | British Medical Journal Publishing Group |
| Publisher Date | 2010-08-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Abortion, Spontaneous Epidemiology Birth Intervals Statistics & Numerical Data Hospitalization Pregnancy Outcome Odds Ratio Pregnancy Pregnancy Complications Retrospective Studies Scotland Comparative Study Multicenter Study Research Support, Non-U.S. Gov't Medicine |
| Content Type | Text |
| Resource Type | Article |
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