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  1. Wiley Interdisciplinary Reviews: Systems Biology and Medicine
  2. Year: 2012 Volume: 4
  3. Year: 2012 Volume: 4 Issue: 3
  4. Isotope labeling experiments in metabolomics and fluxomics.
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Year: 2016 Volume: 8
Year: 2015 Volume: 7
Year: 2014 Volume: 6
Year: 2013 Volume: 5
Year: 2012 Volume: 4
Year: 2012 Volume: 4 Issue: 6
Year: 2012 Volume: 4 Issue: 5
Year: 2012 Volume: 4 Issue: 4
Year: 2012 Volume: 4 Issue: 3
The virtual liver: a multidisciplinary, multilevel challenge for systems biology.
Multiscale models of thrombogenesis.
Diverse functional networks of Tbx3 in development and disease.
Establishing the stem cell state: insights from regulatory network analysis of blood stem cell development.
Linking genome to epigenome.
Theoretical insights into bacterial chemotaxis.
Isotope labeling experiments in metabolomics and fluxomics.
Year: 2012 Volume: 4 Issue: 2
Year: 2012 Volume: 4 Issue: 1
Year: 2011 Volume: 3
Year: 2010 Volume: 2
Year: 2009 Volume: 1

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Isotope labeling experiments in metabolomics and fluxomics.

Content Provider World Health Organization (WHO)-Global Index Medicus
Author Klein, Sebastian Heinzle, Elmar
Description Country affiliation: Germany Author Affiliation: Klein S ( Biochemical Engineering Institute, Saarland University, Saarbrücken, Germany.)
Abstract Metabolomics, the study of all the small molecules in and outside a cell and fluxomics, comprising all conversion rates in a cell, are increasingly used in fundamental and applied sciences to unravel structures and activities of cellular networks and their regulation, to investigate mechanisms of diseases and toxicity, and to improve producing strains among other applications. For both fluxomics and metabolomics the application of isotopes became almost indispensable. Their use in these techniques is discussed, focusing primarily on studies applying stable isotopes and using mass spectrometry. This includes the underlying principles, experimental and computational methods used, and examples of application.
File Format HTM / HTML
ISSN 19395094
Issue Number 3
Volume Number 4
e-ISSN 1939005X
Journal Wiley Interdisciplinary Reviews: Systems Biology and Medicine
Language English
Publisher Wiley
Publisher Date 2012-05-01
Publisher Place United States
Access Restriction Subscribed
Subject Keyword Discipline Computational Biology Metabolomics Chromatography, High Pressure Liquid Gas Chromatography-mass Spectrometry Glucose Metabolism Humans Isotope Labeling Magnetic Resonance Spectroscopy Mass Spectrometry Metabolome Journal Article Review
Content Type Text
Resource Type Article
Subject Medicine Biochemistry, Genetics and Molecular Biology
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