NDLI: RNA dynamics: perspectives from spin labels.

Please wait, while we are loading the content...

RNA dynamics: perspectives from spin labels.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Nguyen, Phuong Qin, Peter Z.
Description	Country affiliation: United States Author Affiliation: Nguyen P ( Department of Chemistry, University of Southern California, Los Angeles, CA, USA.)
Abstract	Dynamics are important and indispensible physical attributes that play essential roles in RNA function. RNA dynamics are complex, spanning vast timescales, and encompassing a large number of physical modes. The technique of site-directed spin labeling (SDSL), which derives information on local structural and dynamic features of a macromolecule by monitoring a chemically stable nitroxide radical using electron paramagnetic resonance spectroscopy, has been applied to monitor intrinsic dynamics at defined structural states as well as to probe conformational transition dynamics of RNAs. The current state of SDSL studies of RNA dynamics is summarized here. Further development and application of SDSL promise to open up many more opportunities for probing RNA dynamics and connecting dynamics to structure and function.
File Format	HTM / HTML
ISSN	17577004
e-ISSN	17577012
DOI	10.1002/wrna.104
Journal	Wiley Interdisciplinary Reviews: RNA
Issue Number	1
Volume Number	3
Language	English
Publisher	Wiley
Publisher Date	2012-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Molecular Biology Chemistry Spin Labels Animals Electron Spin Resonance Spectroscopy Hiv Long Terminal Repeat Nitrogen Oxides Rna, Catalytic Research Support, N.i.h., Extramural Research Support, U.s. Gov't, Non-p.h.s.
Content Type	Text
Resource Type	Article
Subject	Molecular Biology Biochemistry

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

A spirocyclohexyl nitroxide amino acid spin label for pulsed EPR spectroscopy distance measurements.

Parametrization, molecular dynamics simulation, and calculation of electron spin resonance spectra of a nitroxide spin label on a polyalanine alpha-helix.

Determination of the distance between two spin labels attached to a macromolecule.

Nitroxide sensing of a DNA microenvironment: mechanistic insights from EPR spectroscopy and molecular dynamics simulations.

15N- and 2H-substituted maleimide spin labels: improved sensitivity and resolution for biological EPR studies.

Probing the structure of membrane proteins with electron spin echo envelope modulation spectroscopy.

Electron Paramagnetic Resonance Spectroscopy of Nitroxide-Labeled Calmodulin

Multifrequency electron spin resonance study of the dynamics of spin labeled T4 lysozyme.

Solute Effects on Spin Labels at an Aqueous-Exposed Site in the Flap Region of HIV-1 Protease

RNA dynamics: perspectives from spin labels.

Similar Documents

A spirocyclohexyl nitroxide amino acid spin label for pulsed EPR spectroscopy distance measurements.

Parametrization, molecular dynamics simulation, and calculation of electron spin resonance spectra of a nitroxide spin label on a polyalanine alpha-helix.

Determination of the distance between two spin labels attached to a macromolecule.

Nitroxide sensing of a DNA microenvironment: mechanistic insights from EPR spectroscopy and molecular dynamics simulations.

15N- and 2H-substituted maleimide spin labels: improved sensitivity and resolution for biological EPR studies.

Probing the structure of membrane proteins with electron spin echo envelope modulation spectroscopy.

Electron Paramagnetic Resonance Spectroscopy of Nitroxide-Labeled Calmodulin

Multifrequency electron spin resonance study of the dynamics of spin labeled T4 lysozyme.

Solute Effects on Spin Labels at an Aqueous-Exposed Site in the Flap Region of HIV-1 Protease

RNA dynamics: perspectives from spin labels.